Team:Valencia Biocampus/modhp

From 2012.igem.org

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Students from our Human Practices subteam have find out that two years before releasing their last product, the Talking Life Device, <i>Talking Life Technologies</i> started to carry out a high number of secret experiments regarding the safety of their uprising new sensing-bacteria. These <b>controversial results</b> have just been released two days ago! Click this <html><a href="https://static.igem.org/mediawiki/2012/8/8d/Talking_Life_Technologies.pdf" target="blank"><b>link</b></a>
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Students from our Human Practices subteam found out that two years before releasing their last product, the Talking Life Device, <i>Talking Life Technologies</i> started to carry out a high number of secret experiments regarding the safety of their uprising new sensing-bacteria. These <b>controversial results</b> have just been released two days ago! Click this <html><a href="https://static.igem.org/mediawiki/2012/8/8d/Talking_Life_Technologies.pdf" target="blank"><b>link</b></a>
</html> to read their report!
</html> to read their report!
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After analyzing it, we have realized that these equation and the parameters used belong to previous studies done in 2010 (1). Since we wanted to test whether these results were true, we have also carried out our own experiments (Table 1) to determine the best data to use and see the possible outcomes. <b>Let’s model Human Practices!</b>
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After analyzing it, we realized that these equations and the parameters used belong to previous studies done in 2010 (1). Since we wanted to test whether these results were true, we have also carried out our own experiments (Table 1) to determine the best data to use and check the possible outcomes. <b>Let’s model Human Practices!</b>
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After using our own data the population dynamics that we have obtained is similar to those from <i>Talking Life Technologies</i> (Figure 4), confirming the worst-case scenario:
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After using our own data the population dynamics we obtained is similar to those from <i>Talking Life Technologies</i> (Figure 4), confirming the worst-case scenario:
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Revision as of 15:06, 25 September 2012



    Modeling for Human Practices


    Students from our Human Practices subteam found out that two years before releasing their last product, the Talking Life Device, Talking Life Technologies started to carry out a high number of secret experiments regarding the safety of their uprising new sensing-bacteria. These controversial results have just been released two days ago! Click this link to read their report!

    After analyzing it, we realized that these equations and the parameters used belong to previous studies done in 2010 (1). Since we wanted to test whether these results were true, we have also carried out our own experiments (Table 1) to determine the best data to use and check the possible outcomes. Let’s model Human Practices!

    Table 1. Data from different sources used to modelllize the population dynamics.
    *Data obtained after several experiments with a cheating plasmid and with no plasmid at all.



    After using our own data the population dynamics we obtained is similar to those from Talking Life Technologies (Figure 4), confirming the worst-case scenario:

    Figure 4. The evolution of both cheater and secretor ("honest") populations
    using our own data.



    So, how could this big company have done something like that? Is our health under their control?

    References:
    [1] Frank, A. (2010) Microbial secretor−cheater dynamics. Phil. Trans. R. Soc. B 365, 2515-2522

    [2] Volkmer, B. and Heinemann, M. (2011) Condition-Dependent Cell Volume and Concentration of Escherichia coli to Facilitate Data Conversion for Systems Biology Modeling. PLoS ONE 6(7): e23126