Team:Grenoble/Modeling/Amplification/Stochastic/results

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iGEM Grenoble 2012

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Goal


In this part we would like to answer 2 questions thanks to the stochastic modeling.

      Is the sensibility given by stochastic modeling the same that in ODE modeling ?
      What is the part of false positives ?
Thanks to those 2 questions we will be able to establish if our device is still performing when we take into account random variations.

Sensibility


The ODE modeling gave 10-6 molecules of CAMPi as the sensibility. This means, if we have 10-6 molecules of CAMP at the initial point, the system will turn on. But this result is given by a deterministic analysis. What happens if we take into account the random phenomena of the bacterium ? Is the sensibility still so good ?

False positives

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