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Team:Grenoble/Modeling/Amplification/Sensitivity
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In addition we know that the maximum number of copies per cell of Arac is 40, thus<img src="https://static.igem.org/mediawiki/2012/0/09/Eq_sens_4.png" alt="" />where<img src="https://static.igem.org/mediawiki/2012/3/35/Eq_sens_5.png" alt="" />Avogadro number and<img src="https://static.igem.org/mediawiki/2012/6/64/Eq_sens_6.png" alt="" />is E. coli volume. Thus, we have <img src="https://static.igem.org/mediawiki/2012/9/97/Eq_sens_7.png" alt="" />. Then, we get the value of <img src="https://static.igem.org/mediawiki/2012/2/2b/Eq_sens_8.png" alt="" />. | In addition we know that the maximum number of copies per cell of Arac is 40, thus<img src="https://static.igem.org/mediawiki/2012/0/09/Eq_sens_4.png" alt="" />where<img src="https://static.igem.org/mediawiki/2012/3/35/Eq_sens_5.png" alt="" />Avogadro number and<img src="https://static.igem.org/mediawiki/2012/6/64/Eq_sens_6.png" alt="" />is E. coli volume. Thus, we have <img src="https://static.igem.org/mediawiki/2012/9/97/Eq_sens_7.png" alt="" />. Then, we get the value of <img src="https://static.igem.org/mediawiki/2012/2/2b/Eq_sens_8.png" alt="" />. | ||
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| + | For the adenylate cyclase, but we assumed that there is less adenylate cyclase in the cell than Arac. Indeed, when there is too much cAMP is inhibits the production of the adenylate cyclase (see reference [6]). | ||
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Revision as of 16:03, 20 September 2012
Classic Odes Parameters
Explanation 1
- Arac and Ca:
where
Avogadro number and
is E. coli volume. Thus, we have 
. Then, we get the value of 
.
For the adenylate cyclase, but we assumed that there is less adenylate cyclase in the cell than Arac. Indeed, when there is too much cAMP is inhibits the production of the adenylate cyclase (see reference [6]).
