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Team:Grenoble/Biology/Notebook/June
From 2012.igem.org
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The amplification system contains a genetic feed forward loop. It acts as a biologic loud filter aiming at reducing false positive outputs. Once amplified and filtered the signal is transmitted to the neighboring bacteria. In this way a noticeable fluorescent emission is generated. <br/> | The amplification system contains a genetic feed forward loop. It acts as a biologic loud filter aiming at reducing false positive outputs. Once amplified and filtered the signal is transmitted to the neighboring bacteria. In this way a noticeable fluorescent emission is generated. <br/> | ||
<br/> | <br/> | ||
| - | <h4>Scheme of the concept</h4> | + | <center> <h4>Scheme of the concept</h4> </center> |
<img src="https://static.igem.org/mediawiki/2012/9/9d/Schema1.png" alt="Scheme of the concept" style="horizontal-align: center;"/> | <img src="https://static.igem.org/mediawiki/2012/9/9d/Schema1.png" alt="Scheme of the concept" style="horizontal-align: center;"/> | ||
| - | <h4>Theoretical response of the device depending on the input signal</h4> | + | <center> <h4>Theoretical response of the device depending on the input signal</h4></center> |
<img src="https://static.igem.org/mediawiki/2012/c/cf/Schema2.png" alt="Theoretical response of the device depending on the input signal" style="horizontal-align: center;"/> | <img src="https://static.igem.org/mediawiki/2012/c/cf/Schema2.png" alt="Theoretical response of the device depending on the input signal" style="horizontal-align: center;"/> | ||
Revision as of 08:49, 6 August 2012
Week 23: June 04th to 10th
During this week we chose the project on which we wanted to work.We decided to create a system which can detect a pathogene, like Staphylococcus aureus, for example.
We intend to build an ultra sensitive detector. The goal is to produce a detector which can hugely amplify a really low input signal. It consists of three modules:
- the first gets the signal
- the second amplifies it
- the third sends the output
The detection module is a membrane receptor that once activated by a biomolecule actuates an amplification loop. The loop enhances the cell response efficiency.
The amplification system contains a genetic feed forward loop. It acts as a biologic loud filter aiming at reducing false positive outputs. Once amplified and filtered the signal is transmitted to the neighboring bacteria. In this way a noticeable fluorescent emission is generated.
Scheme of the concept
Theoretical response of the device depending on the input signal
