Team:Grenoble/Modeling/Amplification/Stochastic/results
From 2012.igem.org
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We would like to evaluate the time needed to get an answer. Once a bacterium has detected a Golden staph, the quorum sensing will allow the propagation of the information. Thus we will be able to get the answer really quickly and visible. | We would like to evaluate the time needed to get an answer. Once a bacterium has detected a Golden staph, the quorum sensing will allow the propagation of the information. Thus we will be able to get the answer really quickly and visible. | ||
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- | We need to establish a time not too small to avoid false negatives and not too long to avoid false positives and to be | + | We need to establish a time not too small to avoid false negatives and not too long to avoid false positives and to be efficient. Indeed, if we take a short time we can miss some visible output signals which are longer to appear. Then we will conclude that nothing has been detected whereas there was something to detect. If we wait too long, some visible output signals can appear whereas there was nothing to detect. This phenomenon is due to the randomness inside the bacterium and espacially because of basal values. |
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Revision as of 09:45, 20 September 2012
Goal
In this part we would like to answer 3 questions thanks to the stochastic modeling.- How much time do we need to wait to get a response ?
- Is the sensitivity given by stochastic modeling the same as in ODE modeling ?
- What is the part of false positives ?