"
Team:Grenoble/Biology/Notebook/June
From 2012.igem.org
(Difference between revisions)
Greghansen (Talk | contribs) |
|||
| Line 16: | Line 16: | ||
We decided to create a system which can detect a pathogene, like Staphylococcus aureus, for example.<br/> | We decided to create a system which can detect a pathogene, like Staphylococcus aureus, for example.<br/> | ||
<br/> | <br/> | ||
| - | We intend to build an ultra sensitive detector. The goal is to produce a detector which can | + | We intend to build an ultra sensitive detector. The goal is to produce a detector which can greatly amplify an extremely low input signal. It consists of three modules:<br/> |
<ol> | <ol> | ||
<li>the first gets the signal</li> | <li>the first gets the signal</li> | ||
Revision as of 09:33, 6 August 2012
Week 23: June 04th to 10th
During this week we chose the project on which we wanted to work.We decided to create a system which can detect a pathogene, like Staphylococcus aureus, for example.
We intend to build an ultra sensitive detector. The goal is to produce a detector which can greatly amplify an extremely low input signal. It consists of three modules:
- the first gets the signal
- the second amplifies it
- the third sends the output
The detection module is a membrane receptor that once activated by a biomolecule actuates an amplification loop. The loop enhances the cell response efficiency.
The amplification system contains a genetic feed forward loop. It acts as a biologic loud filter aiming at reducing false positive outputs. Once amplified and filtered the signal is transmitted to the neighboring bacteria. In this way a noticeable fluorescent emission is generated.
Scheme of the concept
Theoretical response of the device depending on the input signal
