Team:Fudan Lux/Safety

1.Would any of your project ideas raise safety issues ？

Every member of our team has at least one year experience or training at regular laboratories in Fudan University before they are recruited into our iGEM team. In the lab training, there are routine biosafety lectures every month which ensures everyone in lab to have enough knowledge about lab-safety and common satety issues. Therefore, our members are all aware of basic safety rules.

Moreover, our projects are well reviewed by several professors in Fudan University to make sure that they are safe and practicable for undergraduate students to proceed. Meanwhile, inside our time, we also have a regular examination about lab-safety issues every week.

In detail, our projects are free of toxic or pathogenic or other harmful microbes. Our experimental objects are E.coli (Top10, DH5α) and tumor cells which is used commonly in labs and they are all in strict control. Our project ideas focus on harmless modifications and rebuilding, never can they cause biosafety problems under such strict and scientific control.

2.Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues?

The biobricks we used had been widely used in iGEM.The biobrick we made is a combination of LOV domain and HTH-motif which are Non-toxic。

3.Is there a local biosafety group, committee, or review board at your institution?

Such group in our life-science college thought what we made was safe to both human and environment.

4.Do you have any other ideas how to deal with safety issues that could be useful for future iGEM competitions?

How could parts, devices and systems be made even safer through biosafety engineering? I think we could add dangerous-sequence-monitoring features to partsregistry.org.