Team:Fudan Lux

Project BIOWAVE As is known to all, negative feedback and time delay can cause oscillation in a pure physical system, such as sounds formed by oscillating air molecules and ripples produced via stirring water. What if the particles of wave are bacteria? In this project, we want to utilize a biological system with the properties of negative feedback and time-lapse to form a macroscopic wave-like pattern that could be visualized by the naked eye. Which the system is made by two parts: the light generator and the light sensor. When the light, which generated by the light generator, is strong enough that could be sensed by the light sensor. The sensor protein could repress the expression of light generator. This signal pathway, which based on light, makes the negative feedback. And the expression of light generator makes the time delay. We believe that with the limited spread of light on the colored plat medium, light output of the bacteria could make a biowave. This is the very first time that bacteria using light as an extracellular signal in synthetic biology. And the form of the oscillation pattern could help us explain a lot of biological problem, like the development of fingers and tones.

Project Bacto-TraffickingIt is about constructing a brand-new biological model using a recently discovered cellular structure termed Tunneling Nanotubes(TNT) and E.coli containing green fluorescent protein. By inducing and stabilizing TNTs between Hela cells, a complex cellular network can be established; then the GFP-marked E.coli are introduced into the Hela cells via electroporation—thereby a new type of biological system is created. Moreover, it is the behavior of the injected E.coli within the Hela cells that we want to study here. Since TNTs formed between cells act as super highways for material transportation, E.coli can move from one cell to another through TNTs. Given the condition that bacteria would tend to choose the most suitable place to live in, in the least energy-consuming way, a distribution pattern thus can be obtained, which has the characteristics of the least increase of entropy. With such a model, we anticipate to simulate certain types of problems in the real life that cannot be solved via simple computation (such as traffic jams among cities) and provide solutions to them.

Project LabCloudProject LabCloud aims to provide a mobile app for iGEMers share their experiments, logs, ideas, files and others in and between teams. It will also provide group’s shared calendar, instruments management and other powerful functions to help iGEMers’ cooperation. At last, it has the Push Notification feather to ensure communication in time.Besides, we create a APP Biobrick Viewer accompany with labcloud to provide a easy access to partsregistry.You will find them on App Store soon and there are free for iGEMers!)

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Lorem ipsum dolor Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Vestibulum tortor quam, feugiat vitae, ultricies eget, tempor sit amet, ante. Donec eu libero sit amet quam egestas semper. Aenean ultricies mi vitae est. Mauris placerat eleifend leo. Quisque sit amet est et sapien ullamcorper pharetra.

Lorem ipsum dolor Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Vestibulum tortor quam, feugiat vitae, ultricies eget, tempor sit amet, ante. Donec eu libero sit amet quam egestas semper. Aenean ultricies mi vitae est. Mauris placerat eleifend leo. Quisque sit amet est et sapien ullamcorper pharetra.