"
Team:UNAM Genomics Mexico/Project/DeeperDescription
From 2012.igem.org
Under Construction
Nanotubes!! |
The logic |
Random info |
Deep Description
Our boolean constructions are two, the AND & OR, for it to form a system, but how we will connect this two operations? With the nanotubes that Bacillus subtilis form.
Why B. subtilis?
We found a paper in which Ben-Yehuda et. al. demostrated that Bacillus subtilis form nanotubes between them, Escherichia coli and Staphylococcus aureus. And they were able to get through a GFP and some other smaller molecules. So, we decided to use this connection to form the principles of a molecular computer. How? The output of the first operation will the input for the next one, and that was what we did. Also, there is not many work in the B. subtilis at the iGEM competition, so we decided to standardize the protocols of competent cells and transformation, and to send biobricks that B. subtilis could transform and integrate for them to work correctly (link al new standar protocol).
-
2011 Gyanendra P. Dubey, Sigal Ben-Yehuda. Intercellular Nanotubes Mediate Bacterial Communication. Cell, 2011; 144 (4): 590 DOI:10.1016/j.cell.2011.01.015
-
2011 Gyanendra P. Dubey, Sigal Ben-Yehuda. Intercellular Nanotubes Mediate Bacterial Communication. Cell, 2011; 144 (4): 590 DOI:10.1016/j.cell.2011.01.015
