Team:OUC-China/Modeling/Overview

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<h1>Overview</h1>
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<h1 style="border:none;">Overview</h1>
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<p><span></span>Our model for ratio sensor and comparator consists of four parts: ODE analysis, parameter sensitivity analysis, parameter sweep, stochastic analysis. ODE analysis is to examine the feasibility of our project, which also provides the foundation for next 3 sections of analysis. Through parameter sensitivity analysis, the vital parameters for the system are distinguished. And we could figure out appropriate ranges of the identified sensitive parameters by parameter sweep. At last, noise analysis based on the fixed ranges of sensitive parameters could simulate the real  conditions in vivo.<br/>
<p><span></span>Our model for ratio sensor and comparator consists of four parts: ODE analysis, parameter sensitivity analysis, parameter sweep, stochastic analysis. ODE analysis is to examine the feasibility of our project, which also provides the foundation for next 3 sections of analysis. Through parameter sensitivity analysis, the vital parameters for the system are distinguished. And we could figure out appropriate ranges of the identified sensitive parameters by parameter sweep. At last, noise analysis based on the fixed ranges of sensitive parameters could simulate the real  conditions in vivo.<br/>
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<a href="https://2012.igem.org/Team:OUC-China/Modeling/ODEModel"><img style="margin-left:80px;" src="https://static.igem.org/mediawiki/2012/0/08/Ouc-modeling-math38.JPG"></a>
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<a href="https://2012.igem.org/Team:OUC-China/Modeling/ParameterSensitivityAnalysis"><img style="margin-left:400px; margin-top: -210px;" src="https://static.igem.org/mediawiki/2012/5/5a/Ouc-modeling-math39.jpg"></a>
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<a href="https://2012.igem.org/Team:OUC-China/Modeling/ParameterSensitivityAnalysis"><img style="margin-left:400px; margin-top: -220px;" src="https://static.igem.org/mediawiki/2012/5/5a/Ouc-modeling-math39.jpg"></a>
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<p style="font-size:90%; margin-left:100px; width:200px;"><a href="https://2012.igem.org/Team:OUC-China/Modeling/ODEModel">Feasibility via ODE simulation</a></p>
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<p style="font-size:90%; margin-left:100px; width:200px;  text-decoration:underline;"><a style="color:#000;" href="https://2012.igem.org/Team:OUC-China/Modeling/ODEModel"><i>Feasibility via ODE simulation</i></a></p>
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<p style="font-size:90%;margin-left:420px; width:200px; margin-top:-20px;"><a href="https://2012.igem.org/Team:OUC-China/Modeling/ParameterSensitivityAnalysis">Figure out sensitive parameters in ternary system based on given parameter set
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<p style="font-size:90%;margin-left:420px; width:200px; margin-top:-20px; text-decoration:underline;"><a style="color:#000;" href="https://2012.igem.org/Team:OUC-China/Modeling/ParameterSensitivityAnalysis"><i>Figure out sensitive parameters in ternary system based on given parameter set</i>
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<a href="https://2012.igem.org/Team:OUC-China/Modeling/ParameterSweep"><img style="margin-left:80px;" src="https://static.igem.org/mediawiki/2012/d/d3/Ouc-modeling-math40.jpg"></a>
<a href="https://2012.igem.org/Team:OUC-China/Modeling/ParameterSweep"><img style="margin-left:80px;" src="https://static.igem.org/mediawiki/2012/d/d3/Ouc-modeling-math40.jpg"></a>
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<a href="https://2012.igem.org/Team:OUC-China/Modeling/NoiseAnalysis"><img style="margin-left:400px; margin-top: -200px;" src="https://static.igem.org/mediawiki/2012/8/8e/Ouc-modeling-math41.JPG"></a>
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<a href="https://2012.igem.org/Team:OUC-China/Modeling/NoiseAnalysis"><img style="margin-left:400px; margin-top: -195px;" src="https://static.igem.org/mediawiki/2012/8/8e/Ouc-modeling-math41.JPG"></a>
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<p style="font-size:90%; margin-left:100px; width:200px;"><a href="https://2012.igem.org/Team:OUC-China/Modeling/ParameterSweep">Sweep important parameters for optimized range</a></p>
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<p style="font-size:90%; margin-left:100px; width:200px; text-decoration:underline;"><a style="color:#000;" href="https://2012.igem.org/Team:OUC-China/Modeling/ParameterSweep"><i>Sweep important parameters for optimized range</i></a></p>
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<p style="font-size:90%;margin-left:430px; width:200px; margin-top:-30px;"><a href="https://2012.igem.org/Team:OUC-China/Modeling/NoiseAnalysis">Noise analysis</a></p>
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<p style="font-size:90%;margin-left:430px; width:200px; margin-top:-30px; text-decoration:underline;"><a style="color:#000;" href="https://2012.igem.org/Team:OUC-China/Modeling/NoiseAnalysis"><i>Noise analysis</i></a></p>
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Latest revision as of 02:17, 25 October 2012

Overview



Our model for ratio sensor and comparator consists of four parts: ODE analysis, parameter sensitivity analysis, parameter sweep, stochastic analysis. ODE analysis is to examine the feasibility of our project, which also provides the foundation for next 3 sections of analysis. Through parameter sensitivity analysis, the vital parameters for the system are distinguished. And we could figure out appropriate ranges of the identified sensitive parameters by parameter sweep. At last, noise analysis based on the fixed ranges of sensitive parameters could simulate the real conditions in vivo.




Feasibility via ODE simulation

Figure out sensitive parameters in ternary system based on given parameter set


Sweep important parameters for optimized range

Noise analysis



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