Lab Safety

Would any of your project ideas raise safety issues in terms of:

Researcher safety

There are a number of standard lab reagents that we require the use of in our project, that are harmful on contact. These include:

Ethidium Bromide Material Safety Data Sheet for Ethidium Bromide Acute: Hazardous when ingested or inhaled, and is an irritant of the skin and eye. Chronic: In the long term exposure can have Carcinogenic, Mutagenic, and Teratogenic effects, and can cause Developmental Toxicity.

Congo Red Material Safety Data Sheet for Congo Red Acute: Hazardous when ingested of inhaled, is an irritant of the eye, and an irritant and sensitizer of the skin. Chronic: In the long term exposure can have Carcinogenic, Mutagenic and Teratogenic effects, and can cause Developmental Toxicity.

TAE buffer

Public safety

Environmental safety

Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues?

Did you document these issues in the Registry?

How did you manage to handle the safety issue?

How could other teams learn from your experience?

Is there a local biosafety group, committee, or review board at your institution?

Yes - we have the Departmental Genetic Modification Safety Officer (DGMSO) and the College Genetic Modification Safety Committee, who must approve of our work before it commences. We complete risk assessments, which must meet UCL Local Rules, and we are all fully trained in lab work and monitored.

If yes, what does your local biosafety group think about your project?

If no, which specific biosafety rules or guidelines do you have to consider in your country?

Do you have any other ideas how to deal with safety issues that could be useful for future iGEM competitions? How could parts, devices and systems be made even safer through biosafety engineering?