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Team:Bielefeld-Germany
From 2012.igem.org
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<h1 align="center">Introducing the iGEM Team Bielefeld 2012</h1> | <h1 align="center">Introducing the iGEM Team Bielefeld 2012</h1> | ||
<div align="center" style="z-index:0;"><object width="450" height="280"><param name="movie" value="http://www.youtube.com/v/HwvumBLdwP8?fs=1&hl=en_GB"></param><param name="allowFullScreen" value="true"></param><param name="allowscriptaccess" value="always"></param><param name="wmode" value="opaque" /><embed src="http://www.youtube.com/v/HwvumBLdwP8?fs=1&hl=en_GB" type="application/x-shockwave-flash" allowscriptaccess="always" allowfullscreen="true" width="450" height="280" wmode="opaque"></embed></object></div> | <div align="center" style="z-index:0;"><object width="450" height="280"><param name="movie" value="http://www.youtube.com/v/HwvumBLdwP8?fs=1&hl=en_GB"></param><param name="allowFullScreen" value="true"></param><param name="allowscriptaccess" value="always"></param><param name="wmode" value="opaque" /><embed src="http://www.youtube.com/v/HwvumBLdwP8?fs=1&hl=en_GB" type="application/x-shockwave-flash" allowscriptaccess="always" allowfullscreen="true" width="450" height="280" wmode="opaque"></embed></object></div> | ||
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| + | <h1 align="center">Our partner and sponsors</h1> | ||
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| + | = Gold sponsors = | ||
| + | |||
| + | <center> | ||
| + | [[File:Promega logo 180x109.gif|link=http://www.promega.com/]] | ||
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| + | </center> | ||
| + | <div style="text-align:justify;"> | ||
| + | Promega Corporation is a leader in providing innovative solutions and technical support to the life sciences industry. The company’s 2,000 products enable scientists worldwide to advance their knowledge in genomics, proteomics, cellular analysis, molecular diagnostics and human identification. Founded in 1978, the company is headquartered in Madison, WI, USA with branches in 15 countries and over 50 global distributors. For more information about Promega, visit www.promega.com. | ||
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| + | <center> | ||
| + | [[Image:Logo merck.jpg|center|link=http://www.merckgroup.com/en/index.html]] | ||
| + | </center> | ||
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| + | Merck is a global pharmaceutical and chemical company with total revenues of € 10.3 billion in 2011, a history that began in 1668, and a future shaped by more than 40,000 employees in 68 countries. Its success is characterized by innovations from entrepreneurial employees. Merck's operating activities come under the umbrella of Merck KGaA, in which the Merck family holds an approximately 70% interest and free shareholders own the remaining approximately 30%. In 1917 the U.S. subsidiary Merck & Co. was expropriated and has been an independent company ever since. | ||
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| + | = Silver sponsors = | ||
| + | {| | ||
| + | |- | ||
| + | [[File:BioCircle.JPG|220px|link=http://www.bio-circle.de/home.html]]] || [http://www.evonik.de [[File:Logo evonik.jpg|300px]]] | ||
| + | |- | ||
| + | |} | ||
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| + | = Bronze sponsors = | ||
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| + | {| | ||
| + | |- | ||
| + | |[http://www.bio.nrw.de/en [[File:Logo bio-nrw.png]]] || [http://www.knauer.net [[File:Logo knauer.jpg|300px]]] || [http://www.iit-biotech.de/ [[File:Logo iit.jpg]]] || [http://www.biometra.de [[File:logo biometra.jpg|250px]]] | ||
| + | |- | ||
| + | |} | ||
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| + | = Our Partner = | ||
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| + | <center> | ||
| + | <html> | ||
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| + | <div> | ||
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| + | <div class="partner"> | ||
| + | <table border="0"> | ||
| + | <tr> | ||
| + | <td><div class="partner_img2"> | ||
| + | <a href="http://www.cebitec.uni-bielefeld.de/" target="_blank"><img src="https://static.igem.org/mediawiki/2011/7/7e/Bielefeld-Germany-CeBiTec.jpg" alt="CeBiTec" /></a> | ||
| + | </div> | ||
| + | </td> | ||
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| + | <td><div class="partner_img2"> | ||
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| + | <a href="http://www.uni-bielefeld.de" target="_blank"><img src="https://static.igem.org/mediawiki/2011/6/68/IgemBielefeld_2011_Logo_uni.jpg" alt="University" /></a> | ||
| + | </div> | ||
| + | </td> | ||
| + | <td><div class="partner_img2"> | ||
| + | | ||
| + | <a href="http://www.uni-bielefeld.de/biologie" target="_blank"><img src="https://static.igem.org/mediawiki/2011/5/53/IgemBielefeld_Logo_biofak.jpg" alt="Bio Fakultät" /></a> | ||
| + | </div> | ||
| + | </td> | ||
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| + | <td><div class="partner_img2"> | ||
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| + | <a href="http://www.techfak.uni-bielefeld.de/web/" target="_blank"><img src="https://static.igem.org/mediawiki/2011/b/b7/Bielefeld-Uniersity-techfak.gif | ||
| + | " alt="Technische Fakulä" /></a> | ||
| + | </div> | ||
| + | </td> | ||
| + | </tr> | ||
| + | </table> | ||
| + | <p><font size=4 align=justify> | ||
| + | |||
| + | </font></p> | ||
</html> | </html> | ||
Revision as of 12:07, 29 August 2012
Our Project - Abstract
The birth control pill is a widespread contraception method. However, large amounts of these modified estrogens leave the body again in urine. The conventional methods in sewage treatment plants are unable to treat waste water sufficiently because the most frequently used estrogen ethinylestradiol is very difficult to break down. As a result, the hormone finds its way into rivers and lakes and accumulates in drinking water with serious consequences for fish and other aquatic life. These range from reproductive and severe developmental disorders to the formation of female sexual characteristics in males. The long-term consequences of increasing estrogen pollution for human beings are still largely unknown. Nonetheless, declining sperm counts and thereby increasing infertility in men living in industrial nations may well relate to this hormonal pollution. In addition, testicular and prostate cancers as well as osteoporosis could be a consequence of overly high concentrations of estrogen in the human body.
The goal of Bielefeld’s iGEM team is to develop a biological filter using immobilized laccases to purify municipal and industrial wastewater from synthetic estrogens and other aromatic compounds. Laccases are copper-containing oxidase enzymes found in many organisms, and one of their properties is the ability to break down a wide range of aromatic and phenolic compounds. For this purpose, genes of various bacterial and eukaryotic laccases should be isolated and expressed in Escherichia coli and Pichia pastoris. The team is aiming to manufacture this enzyme economically and safely with the help of methods from synthetic biology. It should also be possible to extend the concept to other, in part poisonous and carcinogenic pollutants in drinking and waste water, as well as into industrial application, such as in paper and textile industries or even for bioremediation of contaminated soil.
Introducing the iGEM Team Bielefeld 2012
Our partner and sponsors
= Gold sponsors =
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