Team:UANL Mty-Mexico/Safety/biobricks

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<p><br><h3>Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues?</h3><br></p>
<p><br><h3>Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues?</h3><br></p>
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<p>The project of this year as well as the past, are based mainly on the use nontoxic/pathogenic parts. Although working with rare BioBrick derivate parts such as Mocr from Ocr (potent inhibitor of DNA restriction and modification enzymes type I of <i>bacteriophage T7</i>), which no longer presents these effects because it have been modified in two amino acids. Also many parts used from bacteriophages are mostly regulatory used and show no damage to team members, general public or the environment.  We worked with <i>E.coli</i> organism level 1, which is well-characterized and present minimal hazard to laboratory personnel or environment.</p>
 
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<p>As mentioned above, is not intended to release the microorganism to the environment (biosensor, chelator and arsenic remover), because much more testing, evidence, techniques and equipment is required, only laboratory and math work will be done for this year. Although it is planned that in a future after having spent enough money and evidence to prove lack of pathogenicity or horizontal transfer of genes and biological locks functioning properly, there is the possibility of using bioremediation in water contaminated with arsenic in major cities of Mexico.</p>
 
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<p>We commit to document and record all parts of this project with all necessary information and clearly specify the parts that may have a conflict with biosafety issues.</p>
 
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<p>The project of this year as well as the past, are <b>based mainly on the use nontoxic/nonpathogenic parts</b>. Although working with rare BioBrick parts such as Mocr derivated from Ocr (potent inhibitor of DNA restriction and modification enzymes type I of <i>bacteriophage T7</i>; (DelProposto, 2009), which no longer presents these effects because it have been modified in two amino acids. Also many parts used from bacteriophages are mostly regulatory used and show no damage to team members, general public or the environment.  We worked with <i>E. coli</i> organism risk 1, which is well-characterized and present minimal hazard to laboratory personnel or environment.</p>
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<p>As mentioned above,<b> it is not intended to release the microorganism to the environment</b> (biosensor, chelator and arsenic remover). Although it is planned that in a future after having spent enough money and evidence to prove lack of pathogenicity or horizontal transfer of genes and biological locks functioning properly, there is the possibility of using bioremediation in water contaminated with arsenic in major cities, industrial and mining fields in Mexico.</p>
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<p>We commit to <b>document and record all parts</b> of this project with all necessary information and clearly specify the parts that may have a conflict with biosafety issues.</p>
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<a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Safety"><li>Overview</a></li>
<a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Safety/project"><li>1. Project ideas</a></li>
<a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Safety/project"><li>1. Project ideas</a></li>
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<a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Safety/biobricks"><li>2. Biobricks</a></li>
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<a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Safety/biobricks"><li><b>>>2. Biobricks</b></a></li>
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<a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Safety/committee"><li>3. Biosafety committee</a></li>
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<a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Safety/committee"><li>3. Committees</a></li>
<a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Safety/ideas"><li>4. Our ideas for safety</a></li>
<a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Safety/ideas"><li>4. Our ideas for safety</a></li>
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<a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Safety/references"><li>5. References</a></li>
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   </ul>  
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Latest revision as of 21:58, 26 September 2012

iGEM UANL 2012


Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues?


The project of this year as well as the past, are based mainly on the use nontoxic/nonpathogenic parts. Although working with rare BioBrick parts such as Mocr derivated from Ocr (potent inhibitor of DNA restriction and modification enzymes type I of bacteriophage T7; (DelProposto, 2009), which no longer presents these effects because it have been modified in two amino acids. Also many parts used from bacteriophages are mostly regulatory used and show no damage to team members, general public or the environment.  We worked with E. coli organism risk 1, which is well-characterized and present minimal hazard to laboratory personnel or environment.


As mentioned above, it is not intended to release the microorganism to the environment (biosensor, chelator and arsenic remover). Although it is planned that in a future after having spent enough money and evidence to prove lack of pathogenicity or horizontal transfer of genes and biological locks functioning properly, there is the possibility of using bioremediation in water contaminated with arsenic in major cities, industrial and mining fields in Mexico.


We commit to document and record all parts of this project with all necessary information and clearly specify the parts that may have a conflict with biosafety issues.


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