"
Team:UANL Mty-Mexico/Project
From 2012.igem.org
| Line 2: | Line 2: | ||
<html> | <html> | ||
<div class="content"> | <div class="content"> | ||
| - | <p><br><h3>Abstract</h3></p> | + | <p><br><h3>Abstract</h3><br></p> |
| + | |||
<p>One of the major environmental problems in northeastern Mexico is arsenic contamination of groundwater. Several projects have previously aimed to biorremediate heavy metals and metalloids using bacteria, but without scalable potential due to the lack of an efficient cell recovery system. | <p>One of the major environmental problems in northeastern Mexico is arsenic contamination of groundwater. Several projects have previously aimed to biorremediate heavy metals and metalloids using bacteria, but without scalable potential due to the lack of an efficient cell recovery system. | ||
We aim to develop an easy-to-recover arsenic biosensor and chelator. Recovery strategy will consist of a new adhesion mechanism that enables bacteria to bind to silica surfaces through the expression of the L2 ribosomal protein, attached to the outer membrane protein AIDA-I. A quantifiable, highly-sensitive luciferase-based reporter system coupled to an oligomeric metallothionein is expected to increase our system’s capability of arsenic sensing and chelation.</p> | We aim to develop an easy-to-recover arsenic biosensor and chelator. Recovery strategy will consist of a new adhesion mechanism that enables bacteria to bind to silica surfaces through the expression of the L2 ribosomal protein, attached to the outer membrane protein AIDA-I. A quantifiable, highly-sensitive luciferase-based reporter system coupled to an oligomeric metallothionein is expected to increase our system’s capability of arsenic sensing and chelation.</p> | ||
| + | |||
| + | <p><h3>Overview</h3></p> | ||
| + | |||
| + | <p>Our project will be divided in three main modules: detection, capture and recovery. Each of them can be used as a separate tool; we are then to construct a biorremediation kit whose parts are potentially useful for other purposes. | ||
| + | </p> | ||
</div> | </div> | ||
<div class="sidebar2"> | <div class="sidebar2"> | ||
<ul class="nav"> | <ul class="nav"> | ||
| - | <a href="#"><li> | + | <a href="#"><li><b>>>Abstract</b></a></li> |
| - | <a href=" | + | <a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Project/detection"><li>Detection</a></li> |
| - | <a href=" | + | <a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Project/capture"><li>Capture</a></li> |
| + | <a href="https://2012.igem.org/Team:UANL_Mty-Mexico/Project/recovery"><li>Recovery</a></li> | ||
</ul> | </ul> | ||
</div> | </div> | ||
</html> | </html> | ||
{{:Team:UANL_Mty-Mexico/Templates:Footer}} | {{:Team:UANL_Mty-Mexico/Templates:Footer}} | ||
Revision as of 00:12, 24 September 2012
Abstract
One of the major environmental problems in northeastern Mexico is arsenic contamination of groundwater. Several projects have previously aimed to biorremediate heavy metals and metalloids using bacteria, but without scalable potential due to the lack of an efficient cell recovery system. We aim to develop an easy-to-recover arsenic biosensor and chelator. Recovery strategy will consist of a new adhesion mechanism that enables bacteria to bind to silica surfaces through the expression of the L2 ribosomal protein, attached to the outer membrane protein AIDA-I. A quantifiable, highly-sensitive luciferase-based reporter system coupled to an oligomeric metallothionein is expected to increase our system’s capability of arsenic sensing and chelation.
Overview
Our project will be divided in three main modules: detection, capture and recovery. Each of them can be used as a separate tool; we are then to construct a biorremediation kit whose parts are potentially useful for other purposes.
