Team:Freiburg/Project

From 2012.igem.org

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(Overall project)
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<div align="justify">Since April 2012, we are working in the field of so called TAL effectors in our lab. TAL effectors are molecular components that are fused to DNA binding proteins in order to restrict their acticvity to specific loci in a genome. In particular, we develop a strategy to cheaply create novel TAL effectors in an extremely short period of time. This new method will enable us to test numerous novel effectors in human cells and to assess their therapeutic potential for genetic diseases, epigenetic alterations and cancer.
<div align="justify">Since April 2012, we are working in the field of so called TAL effectors in our lab. TAL effectors are molecular components that are fused to DNA binding proteins in order to restrict their acticvity to specific loci in a genome. In particular, we develop a strategy to cheaply create novel TAL effectors in an extremely short period of time. This new method will enable us to test numerous novel effectors in human cells and to assess their therapeutic potential for genetic diseases, epigenetic alterations and cancer.
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We hope you will leran something about our project and the power of TAL effectors.
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== [[Team:Freiburg/HumanPractices/Philo|1. Building the Toolkit]]==
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<p><div style="color: #1C649F; font-size: 16px;font-family: Gill Sans MT; text-indent:30px;">Learn about the theory behind the TAL effector toolkit, how we created it and why we choose this design.</div>
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==[[Team:Freiburg/HumanPractices/Education|2. Using the Toolkit]]==
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<div style="color: #1C649F; font-size: 16px;font-family: Gill Sans MT; text-indent:30px;">Create your own is the inoffical motto of our toolkit, we know how to use it, but we want you to know.</div>
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<div style="color: #1C649F; font-size: 16px;font-family: Gill Sans MT; text-indent:30px;">Read this instruction and start working with the toolkit yourself.</div>
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==[[Team:Freiburg/HumanPractices/Outreach|3. The future of TAL]]==
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<div style="color: #1C649F; font-size: 16px;font-family: Gill Sans MT; text-indent:30px;">TAL effectors are so new that we cant even talk about a history of TAL, but we should talk about</div>
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<div style="color: #1C649F; font-size: 16px;font-family: Gill Sans MT; text-indent:30px;">their future. Our toolkit is not just easy to use but also its easy to automatable, we can proof that our kit is </div>
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<div style="color: #1C649F; font-size: 16px;font-family: Gill Sans MT; text-indent:30px;">easiely workable by a robot</div>
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<iframe width="560" height="315" style="margin-left:100px; margin-top:20px ;margin-bottom:0;"src="http://player.vimeo.com/video/49902809" width="400" height="300" frameborder="0" webkitAllowFullScreen mozallowfullscreen allowFullScreen></iframe>
 
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<!--- The Mission, Experiments --->
<!--- The Mission, Experiments --->

Revision as of 17:36, 25 September 2012




Project FreigembarNEWBRIGHT.jpg



Overall project

Since April 2012, we are working in the field of so called TAL effectors in our lab. TAL effectors are molecular components that are fused to DNA binding proteins in order to restrict their acticvity to specific loci in a genome. In particular, we develop a strategy to cheaply create novel TAL effectors in an extremely short period of time. This new method will enable us to test numerous novel effectors in human cells and to assess their therapeutic potential for genetic diseases, epigenetic alterations and cancer.

We hope you will leran something about our project and the power of TAL effectors.


1. Building the Toolkit

Learn about the theory behind the TAL effector toolkit, how we created it and why we choose this design.


2. Using the Toolkit

Create your own is the inoffical motto of our toolkit, we know how to use it, but we want you to know.
Read this instruction and start working with the toolkit yourself.


3. The future of TAL

TAL effectors are so new that we cant even talk about a history of TAL, but we should talk about
their future. Our toolkit is not just easy to use but also its easy to automatable, we can proof that our kit is
easiely workable by a robot