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Team:Arizona State/Problem
From 2012.igem.org
Detailed Problem Description
What is the problem we want to solve
Viewed as a minor inconvenience in the developed world, diarrhea can be a death sentence in developing countries. Diarrhea can be life threatening as it causes severe dehydration as a result of extensive fluid loss. An estimated 2.0 billion cases of diarrhea occur each year amongst children under five years of age. Of these cases, 1.5 million children die. The major pathogens that most frequently cause acute childhood diarrhea cases are bacterial pathogens such as E. coli, Shigella, Campylobacter and Salmonella. The ASU iGEM team plans to develop an inexpensive way for communities to test the purity of water sources- and identify the specific pathogens in the water source- in efforts of reducing the incidence of childhood diarrhea and ultimately decreasing mortality rates.
Quantitative considerations
...What concentration of pathogens causes sickness?
...What specific design approaches did we take to try to reduce false positives, while making the biosensor effective?
Why are we doing this?
...what do we hope to accomplish/want to figure out?
...who are we doing this for? what do we care about? tie in to human practices and provide links
...what is our ultimate goal?
How we are doing it
...what are our methods?
...How is this different compared what others have done?
...what has already been tried?
