Team:UCSF/Modeling

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Modeling of the Auxotroph System

**A summary of our modeling work is shown on this page and a detailed analysis can be downloaded HERE


Our goal is to get a steady ratio of the two strains’ populations, which is neither too large nor too small. Firstly, we did mathematical analysis based on the ODEs above; then we did simulation of this system. What’s more, we also searched suitable parameters which could make the system go to a steady ratio of the two strains to test the robustness of this system. At last, we did a sensitivity analysis which could tell us which parameter is sensitive if we want to get a steady ratio.

Reference
[1] Alissa Kerner, Jihyang Park, Audra Williams, Xiaoxia Nina Lin “A Programmable Escherichia coli Consortium via Tunable Symbiosis”,Plos One, March 2012 | Volume 7 | Issue 3 | e34032.

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