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From 2012.igem.org

Detailed Problem Description

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What is the problem we want to solve

...how can you have a project without a problem? Dr. Haynes: the problem is detecting invisible signal in a water sample. You have to detect and amplify in a way that is cost effective and easy to use, right?
...be more detailed than Abstract/Overview
...to Abhi: what is the difference between Abstract and Overview?

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Quantitative considerations

...What concentration of pathogens causes sickness?
...What specific design approaches did we take to try to reduce false positives, while making the biosensor effective?

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Why are we doing this?

...what do we hope to accomplish/want to figure out?
...who are we doing this for? what do we care about? tie in to human practices and provide links
...what is our ultimate goal?

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How we are doing it

...what are our methods?
...How is this different compared what others have done?
...what has already been tried?