Team:UANL Mty-Mexico/hp/tunnel

Synthetic Biology Tunnel

The Synthetic Biology (SynBio) Tunnel is a project to massively inform the crowd. We gave people of all ages accurate information to understand what SynBio is and how it is carried out. In about 50 minutes and across ten interactive modules, we covered topics from basic molecular biology to applications of SynBio and iGEM. Our objective is to educate people in the area in order to promote a founded, critic judgment; very likely to improve SynBio social acceptance.

1: DNA

Topics: -DNA as the information storage molecule in all living things. -Organization of DNA within cells. -Molecular structure of DNA -DNA structure model. Activity: Puzzle board game to learn how DNA is copied.

2: Genes

Topics: -Genes as functional units of DNA -Organization and parts of a genes -How do the genes work? -Central dogma of molecular biology.  Activity: Puzzle with multiple options to explain gene function through the central Dogma. -Use of common examples.

3: Proteins

Topics: -Proteins as carriers of most biological processes -Types of proteins -Examples of  common proteins -The genetic code  Activity: Build a protein from DNA code (translation), Protein models.

4: Genetic Engineering

Topics: -Recombinant DNA technology -Restriction enzymes, ligase and vectors -Examples.  Activity: Build a recombinant DNA molecule with colored cables  and transform a cell.

5: Synthetic Biology

Topics: -Universality, modularity and abstraction of bioparts -Synbio as the application of engineering concepts to biology -Advancements in DNA synthesis and sequencing technologies. Activity:  Construct a genetic circuit on a board and estimate time and costs to build it.

6: Biobricks

Topics: -BioBricks as standard DNA parts - Parts of a BioBrick - Types of BioBricks. -Biobrick assembly -The Registry of Standard Biological Parts Activity: Put compatible bricks together.

7: Biological machine

Topics: -Imagine the possibilities -Addressing high impact problems through biomachines. -Metabolic load -Advantages of biomachines over robots. Activity: "Labyrinth of metabolism" so that the visitor knows that "parts" must be manipulated to make a organism perform certain function.

8: Applications of SynBio

Topics: -Impact of SynBio in a wide variety of areas - Examples of issues solved through SynBio (How do these projects work?)  Activity: The visitor must correlate a specific genetic circuit to its application area.

9: iGEM

Topics: iGEM as the biggest synthetic biology competition, rules, motivation, scope. - iGEM UANL 2011 and 2012 -CIDEB-UANL 2012  Activity: -Explain our 2011 project (LINK) -Exhibition of the light-machine used in our project -Explain CIDEB's 2012 project (LINK)

10: Ethics and Biosafety

Topics: -Ethics definition -Human quality of life -Good and ugly -Impact awareness -Acceptance of SynBio -Potential problems -Precautions taken to prevent them -Biosafety levels Activity: Dress with biosafety equipment  (lab coat, glasses, gloves…) as fast as possible!