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From 2012.igem.org

Project

Overall project

Since April 2012, we are working in the field of so called TAL effectors in our lab. TAL effectors are molecular machines that are fused to DNA binding proteins in order to restrict their acticvity to specific loci in a genome. In particular, we develop a strategy to cheaply create novel TAL effectors in an extremely short period of time. This new method will enable us to test numerous novel effectors in human cells and to assess their therapeutic potential for genetic diseases, epigenetic alterations and cancer.