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The ultimate goal of the University of Illinois 2012 iGEM team is to construct an RNA based protein scaffold to use in the optimization of multi-step enzymatic pathways like that involved in the production of Piceatannol from less complex molecules. We aim to improve the versatility and cost efficiency of biological production systems by use of our PUF project RNA scaffold and to prove its viability through the implementation of such a system in our PHAT project's Piceatannol production in E.Coli. Click here to read our project abstract.
In developing a protein based RNA binding toolkit, researchers will be able to transmute the biobricked PUF to do what is necesary for their scientific endeavors. We seek to standardize and characterize the nature of PUF and prove its versatility and viability in being acting as the foundation of our toolkit.
How?
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