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Team:HKUST-Hong Kong/Design Module
From 2012.igem.org
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<h1><p align=center>Regulation and Control Module</p></h1> | <h1><p align=center>Regulation and Control Module</p></h1> | ||
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| - | <p>Our module aims at regulating the growth of our engineered bacteria B. hercules and the production of the anti-tumor drug. We first introduce a xylose inducible promoter, which can help us control the timing of anti-tumor drug expression and secretion. Our choice of xylose as an inducer stems from its induction efficiency is attributed to its little existence and low absorption rate in colon......<a href="https://2012.igem.org/Team:HKUST-Hong_Kong/Module/Regulation_and_control">click here to see more</a></p> | + | <p>Our module aims at regulating the growth of our engineered bacteria B. hercules and the production of the anti-tumor drug, BMP2. We first introduce a xylose inducible promoter, which can help us control the timing of anti-tumor drug expression and secretion. Our choice of xylose as an inducer stems from its induction efficiency is attributed to its little existence and low absorption rate in colon......<a href="https://2012.igem.org/Team:HKUST-Hong_Kong/Module/Regulation_and_control">click here to see more</a></p> |
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Revision as of 16:00, 26 September 2012
Design - Module
Target Binding Module
Our decision to pursue colorectal carcinoma suppression arose from two key points obtained from preliminary research: 1) bone morphogenetic protein 2 (BMP2) suppresses the growth of colon cancer cell growth in vivo, and 2) the phage display peptide RPMrel confers specific and preferential binding to non-differentiated colon cancer cells......Click to see more
Anti-tumor Molecule Secretion Module
As our team objective is to provide a specific and efficient drug delivery for Colon cancer, ivestigating and designing the way of drug synthesis and releasing is a significant part of our whole project. Hence this module is focusing on the production and delivery of anti-tumor drug......click to see more
Regulation and Control Module
Our module aims at regulating the growth of our engineered bacteria B. hercules and the production of the anti-tumor drug, BMP2. We first introduce a xylose inducible promoter, which can help us control the timing of anti-tumor drug expression and secretion. Our choice of xylose as an inducer stems from its induction efficiency is attributed to its little existence and low absorption rate in colon......click here to see more
