"
Team:HKUST-Hong Kong/Module
From 2012.igem.org
| Line 322: | Line 322: | ||
<h1><p align=center>Target Binding Module</p></h1> | <h1><p align=center>Target Binding Module</p></h1> | ||
</div> | </div> | ||
| - | <p> | + | <p>Our decision to pursue colorectal carcinoma suppression arose from two key points obtained from preliminary research: 1) bone morphogenetic protein 2 (BMP-2) suppresses the growth of colon cancer cell growth <i>in vivo</i>, and 2) the phage display peptide RPMrel confers specific and preferential binding to non-differentiated colon cancer cells......<a href="https://2012.igem.org/Team:HKUST-Hong_Kong/Module/Target_binding">Click to see more</a></p> |
</div> | </div> | ||
<div id="paragraph2" class="bodyParagraphs"> | <div id="paragraph2" class="bodyParagraphs"> | ||
Revision as of 16:36, 24 September 2012
MODULE
Target Binding Module
Our decision to pursue colorectal carcinoma suppression arose from two key points obtained from preliminary research: 1) bone morphogenetic protein 2 (BMP-2) suppresses the growth of colon cancer cell growth in vivo, and 2) the phage display peptide RPMrel confers specific and preferential binding to non-differentiated colon cancer cells......Click to see more
Anti-tumor Molecule Secretion Module
As our team objective is to provide a specific and efficient drug for Colon cancer, the way of drug synthesis and releasing is a significant part of our whole project. Hence this module is focusing on the production and delivery of anti-tumor drug......click to see more
Regulation and Control Module
Our module aims at regulating our synthetic bacteria B. hercules. We first introduce a xylose inducible promoter, which can help us control the timing of BMP-2 expression. Our choice of xylose as an inducer stems from its induction efficiency, its little existence and low absorption rate in colon......click here to see more
