Team:KAIST Korea/Project Future
From 2012.igem.org
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<span id="little"><span id='starter'>I</span>n this system, a gene expressing pollutant sensor protein is initially generated due to its promoter orientation. When pollutant sensor detects pollutants, it will initiate the expression of integrase. Then, integrase will recognize and invert the orientation of promoter sequence. Now, scavenger proteins will be expressed and start to remove pollutants. Meanwhile, GFP will be expressed as well to let us know that pollutants are being degraded. In the end, exisionase will be expressed, which will in turn retrieve the initial orientation of promoter. </span></br></br> | <span id="little"><span id='starter'>I</span>n this system, a gene expressing pollutant sensor protein is initially generated due to its promoter orientation. When pollutant sensor detects pollutants, it will initiate the expression of integrase. Then, integrase will recognize and invert the orientation of promoter sequence. Now, scavenger proteins will be expressed and start to remove pollutants. Meanwhile, GFP will be expressed as well to let us know that pollutants are being degraded. In the end, exisionase will be expressed, which will in turn retrieve the initial orientation of promoter. </span></br></br> | ||
<span id="little2">This is just a ‘concept’ up to this point. However, we still view our concept valuable since these little sensors and scavengers would work as guardians of the environment. Bacteri-Guard has some advantages over conventional sensors. When ordinary sensors notice toxic compounds or pollutants, scavengers are expressed but their expression rate does not vary while the amount of pollutants varies. This may cause stress and eventually be harmful to cells. However, Bacteri-Guard is capable of adjusting expression of scavenger molecules and turning them on or off. This is the major excellence of our module and through this we can avoid unwanted stress toward cells. To simply put, with our module, we can take care of the environment and relieve the stress of host cell in automatic manner. Allowing natural recovery, this is the beauty of our module and <b>‘Bacteri-Guard’</b>.</span></br></br> | <span id="little2">This is just a ‘concept’ up to this point. However, we still view our concept valuable since these little sensors and scavengers would work as guardians of the environment. Bacteri-Guard has some advantages over conventional sensors. When ordinary sensors notice toxic compounds or pollutants, scavengers are expressed but their expression rate does not vary while the amount of pollutants varies. This may cause stress and eventually be harmful to cells. However, Bacteri-Guard is capable of adjusting expression of scavenger molecules and turning them on or off. This is the major excellence of our module and through this we can avoid unwanted stress toward cells. To simply put, with our module, we can take care of the environment and relieve the stress of host cell in automatic manner. Allowing natural recovery, this is the beauty of our module and <b>‘Bacteri-Guard’</b>.</span></br></br> | ||
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+ | <img id="starter-grad" style="height:60px;" src="https://static.igem.org/mediawiki/2012/9/95/Starter_gradient_kaist.png"></img> | ||
+ | <h1>Auto-regulated production of 1,4-BDO</h1> | ||
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+ | </br> | ||
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<img src="https://static.igem.org/mediawiki/2012/c/cc/KAIST_Future_plan.PNG"/></br></br> | <img src="https://static.igem.org/mediawiki/2012/c/cc/KAIST_Future_plan.PNG"/></br></br> | ||
<span id="little"> | <span id="little"> |
Revision as of 19:30, 26 October 2012
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2012 KAIST Korea
Mail : kaist.igem.2012@gmail.com
Twitter : twitter.com/KAIST_iGEM_2012
Facebook : www.facebook.com/KAISTiGEM2012
Project : Future Plan
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Bacteri-Guard
As our future plan, we came up with this system, Bacteri-Guard. Let’s see how it works.![](https://static.igem.org/mediawiki/2012/9/95/Starter_gradient_kaist.png)