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Team:UANL Mty-Mexico/Modeling/Silica binding
From 2012.igem.org
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<p><br><h2>Silica binding</h2></br></p> | <p><br><h2>Silica binding</h2></br></p> | ||
| - | <p>The silica binding module of our project is based on the expression of a chimeric transmembranal protein, OmpA-L2. This chimeric protein is composed by | + | <p>The silica binding module of our project is based on the expression of a chimeric transmembranal protein, OmpA-L2. This chimeric protein is composed by an OmpA domain (the transmembranal domain) and a L2 domain (the silica binding domain). |
</p> | </p> | ||
| - | <p>For the mathematical representation of the binding to silica particles, we work at the population level and take into account a | + | <p>For the mathematical representation of the binding to silica particles, we work at the population level and take into account a Verhulst logistic function to describe the kinetics of this process. We assume that bacteria are in the stationary phase and that the first binding of a bacterial cell to a silica particle occurs in a faster timescale, so that we can safely assume that it occurs immediately. Finally, the size of the particles is assumed to be greater than that of the cells. |
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Revision as of 05:59, 26 September 2012
Silica binding
The silica binding module of our project is based on the expression of a chimeric transmembranal protein, OmpA-L2. This chimeric protein is composed by an OmpA domain (the transmembranal domain) and a L2 domain (the silica binding domain).
For the mathematical representation of the binding to silica particles, we work at the population level and take into account a Verhulst logistic function to describe the kinetics of this process. We assume that bacteria are in the stationary phase and that the first binding of a bacterial cell to a silica particle occurs in a faster timescale, so that we can safely assume that it occurs immediately. Finally, the size of the particles is assumed to be greater than that of the cells.
