Template:Team:XMU-China/safety

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<p align="center" class="tit"><strong>SAFETY</strong></p>
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        <p align="center"><strong class="tit">SAFETY</strong></p>
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        <p><strong class="subtitle"><a name="Toc01" id="Toc01"></a>Researcher, Public and Environmental Safety </strong><br>
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          The genetic materials used in our  project pose no safety or health concerns to members in the laboratory. There  were certain chemicals and solvents we used in laboratory that are known to be  toxic such as ethidium bromide, but all were treated with proper caution  and care. We strictly followed the<strong> BSL-1</strong> requirements. All biological  wastes and equipments that have physical contacts with biological samples were  bleached that was optional and autoclaved before disposal and reuse. If released by accident, our parts and  materials would do some negative damage to the general public. Our BioBrick parts or devices might raise the resistance of<em> <strong>Escherichia  coli </strong></em>to certain antibiotics. As we were not conducting large-scale  proliferation of microorganisms, the leakage of the bacteria cultured for  testing experiments would not have significant impact on the general safety of  the environment. However, we strictly followed the <strong>BSL-1</strong> requirements as mentioned above and avoided any release of the  BioBrick parts or devices or microorganisms to the environment. <strong> </strong></p>
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        <p align="left">The environment was also in no danger  from such a hypothetical release for reasons stated previously. Also, model organisms used in our project included<strong><em> Escherichia  coli</em> BL21 and DH5α</strong>.  They are non-virulent strains which are commonly used in microbiology  laboratories. </p>
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        <p align="left">Besides, there would be no risks to security through  malicious misuse by individuals, groups or states. Any malicious misuse of  BioBrick parts or devices or microorganisms might have great threat to  security. To avoid these potential hazards, we have carefully handled our  experiments, stored our materials and products. Human error and poor technique could  compromise the best of safeguards to protect the researcher and cause unpredicted  risks to both human and environment. For this reason, we have conducted a  continuous training in safety measures for all 2012 XMU-China team members and  other laboratory workers in our laboratory.</p><hr>
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        <p align="left"><strong class="subtitle"><a name="Toc02"></a>Biosafety  Standards and Institutions</strong><br>
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          Xiamen University has its own biosafety rules that are  regulated by the Ministry of Environment Protection, P.R. China and our  institution. We carried out our experiments and evaluated bio-safety issues in  our iGEM project strictly according to the Chinese Pathogenic Microbiology  Laboratory Bio-safety Regulations, 2004, P.R. China. </p>
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        <p>Link to the Nation Biosafety Office: <br>
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          <a href="http://english.biosafety.gov.cn/">National Biosafety Office</a><sup><a href="#_ENREF_1" title="Ron Weiss, 2003 #2">[1]</a></sup></p>
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        <p>Link to the regulations: <br>
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          <a href="http://www1.www.gov.cn/zwgk/2005-05/23/content_256.htm">Biosafety  regulation on pathogenic microbes</a> <sup><a href="#_ENREF_2" title="Ron Weiss, 2003 #2">[2]</a></sup><u> </u></p><hr>
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        <p><strong class="subtitle"><a name="Toc03"></a>Biosafety Training</strong><br>
 +
          Every member of our laboratory received biosafety training before  the project began. It included general laboratory safety, biosafety and  hazardous and chemical spill training. These training sessions were put on by  the code of practice and the local guidelines, and including the safety and  operations manual as well. Furthermore, every member of the iGEM team was  trained by our iGEM graduate student instructors on proper laboratory  techniques and safety procedures.</p><hr>
 +
        <p><strong class="subtitle"><a name="Toc04"></a>Future Safety and Security Suggestions</strong><br>
 +
          Since there was a <strong>Potential  Risk </strong>that if released by accident, our parts and  materials would do some negative damage to the general public. Our BioBrick parts or devices might raise the resistance of<em> <strong>Escherichia  coli</strong></em> to certain antibiotics. We suppose that we could design a  mechanism into bacterium or add a device which can dissolve the released  reagents.</p>
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        <p>In addition, we believe that collecting the safety concerns and  information into a biosafety criterion book and making it become one of the  criteria would improve adherence to biosafety regulations.</p><hr>
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        <p><strong class="subtitle"><a name="Toc05"></a>References</strong><br>
 +
          <a name="_ENREF_1" id="_ENREF_1">[1]U.S Department of Health and Human Services, Biosafety in  Microbiological and Biomedical Laboratories, Fifth Edition, US Government  Printing Office, <strong>2007</strong></a></p>
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        <p><a name="_ENREF_2" id="_ENREF_2">[2]World Health Organization, Laboratory Biosafety Manual, Third Edition,  <strong>2004</strong></a></p>
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<p class="subtitle"><a name="_Toc334813185" id="_Toc334813185"></a> Researcher, Public and Environmental Safety &shy;</p>
 
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  <p>The genetic materials used in our project pose no safety  or health concerns to members in the laboratory. There were certain chemicals and solvents we used in laboratory that are  known to be toxic such as ethidium bromide, but they were all treated with proper caution and care. We strictly followed the<strong> BSL-1</strong> requirements. All biological wastes and equipments that have physical contacts  with biological samples were bleached that was optional and autoclaved before disposal and reuse. If released by accident, our parts and materials  would do some negative damage to the general public. Our  BioBrick parts or devices might raise the resistance  of <strong>Escherichia coli</strong> to certain antibiotics. As we were not conducting large-scale proliferation of microorganisms, the leakage of  the bacteria cultured for testing experiments would not have significant impact  on the general safety of the environment. However, we strictly followed the <strong>BSL-1</strong> requirements as mentioned above and avoided any release of the BioBrick  parts or devices or microorganisms to the environment. <br />
 
-
  The environment was also in no danger from such a hypothetical release  for reasons stated previously. Also, model organisms used  in our project included<strong> </strong><strong>Escherichia coli</strong><strong> </strong><strong>BL21</strong><strong> and DH5</strong><strong>&alpha;</strong>.  They are non-virulent strains which are commonly used in microbiology  laboratories. <br />
 
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Besides,  there would be  no risks to security through malicious misuse by individuals, groups or states.  Any malicious misuse of BioBrick parts or devices or  microorganisms might have great threat to security. To avoid these potential  hazards, we have carefully handled our experiments, stored our materials and  products. Human error and poor technique could compromise the best of safeguards to protect the researcher and cause  unpredicted risks to both human and environment. For this reason, we have  conducted a continuous training in safety measures for all 2012 XMU-China team  members and other laboratory workers in our laboratory.</p><hr />
 
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<p class="subtitle"><a name="_Toc334813186" id="_Toc334813186"></a>Biosafety Standards and Institutions</p> <p>
 
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  Xiamen University has its own biosafety rules that are regulated by  the Ministry of Environment Protection, P.R. China and our institution. We carried  out our experiments and evaluated bio-safety issues in our iGEM project strictly according to the Chinese Pathogenic  Microbiology Laboratory Bio-safety Regulations, 2004, P.R. China. <br />
 
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  Link to the Nation Biosafety  Office: <br />
 
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  <a href="http://english.biosafety.gov.cn/" style="text-decoration:underline">National Biosafety Office</a><br />
 
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Link to the regulations: <br />
 
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<a href="http://www1.www.gov.cn/zwgk/2005-05/23/content_256.htm" style="text-decoration:underline">Biosafety regulation on pathogenic microbes</a></p>
 
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<hr />
 
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<p class="subtitle"><a name="_Toc334813187" id="_Toc334813187"></a><strong>Biosafety Training</strong> </p>
 
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<p>
 
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Every member of our laboratory received biosafety training before the project began. It included general laboratory safety, biosafety  and hazardous and chemical spill training. These training sessions were put on by the code of practice and the local guidelines, including the  safety and operations manual as well.&nbsp;  Furthermore, every member of the iGEM team was  trained by our iGEM graduate student instructors on  proper laboratory techniques and safety procedures.</p><hr />
 
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<p class="subtitle"><a name="_Toc334813188" id="_Toc334813188"></a><strong>Future Safety and Security  Suggestions</strong></p>
 
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  <p>Since there was a <strong>Potential Risk </strong>that if released by  accident, our parts and materials would do some negative damage to the general public. Our BioBrick  parts or devices might raise the resistance of <strong>Escherichia coli</strong> to  certain antibiotics. We suppose that we could design a mechanism into bacterium  or add a device which can dissolve the released reagents.&nbsp; <strong> </strong><br />
 
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&nbsp;In addition, we believe that collecting the safety concerns and information into a biosafety criterion book and making it become one of the  criteria would improve adherence to biosafety regulations.</p>
 
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Latest revision as of 02:00, 26 September 2012

XMU-CSS

XMU

safetyindex

Contents[hide][show]
  • Researcher, Public and Environmental Safety
  • Biosafety Standards and Institutions
    		•
  • Biosafety Training
  • Future Safety and Security Suggestions
    		•
  • References
    		•

    XMU-SAFETY

    SAFETY

    Researcher, Public and Environmental Safety
    The genetic materials used in our project pose no safety or health concerns to members in the laboratory. There were certain chemicals and solvents we used in laboratory that are known to be toxic such as ethidium bromide, but all were treated with proper caution and care. We strictly followed the BSL-1 requirements. All biological wastes and equipments that have physical contacts with biological samples were bleached that was optional and autoclaved before disposal and reuse. If released by accident, our parts and materials would do some negative damage to the general public. Our BioBrick parts or devices might raise the resistance of Escherichia coli to certain antibiotics. As we were not conducting large-scale proliferation of microorganisms, the leakage of the bacteria cultured for testing experiments would not have significant impact on the general safety of the environment. However, we strictly followed the BSL-1 requirements as mentioned above and avoided any release of the BioBrick parts or devices or microorganisms to the environment.

    The environment was also in no danger from such a hypothetical release for reasons stated previously. Also, model organisms used in our project included Escherichia coli BL21 and DH5α. They are non-virulent strains which are commonly used in microbiology laboratories.

    Besides, there would be no risks to security through malicious misuse by individuals, groups or states. Any malicious misuse of BioBrick parts or devices or microorganisms might have great threat to security. To avoid these potential hazards, we have carefully handled our experiments, stored our materials and products. Human error and poor technique could compromise the best of safeguards to protect the researcher and cause unpredicted risks to both human and environment. For this reason, we have conducted a continuous training in safety measures for all 2012 XMU-China team members and other laboratory workers in our laboratory.

    Biosafety Standards and Institutions
    Xiamen University has its own biosafety rules that are regulated by the Ministry of Environment Protection, P.R. China and our institution. We carried out our experiments and evaluated bio-safety issues in our iGEM project strictly according to the Chinese Pathogenic Microbiology Laboratory Bio-safety Regulations, 2004, P.R. China.

    Link to the Nation Biosafety Office:
    National Biosafety Office[1]

    Link to the regulations:
    Biosafety regulation on pathogenic microbes [2]

    Biosafety Training
    Every member of our laboratory received biosafety training before the project began. It included general laboratory safety, biosafety and hazardous and chemical spill training. These training sessions were put on by the code of practice and the local guidelines, and including the safety and operations manual as well. Furthermore, every member of the iGEM team was trained by our iGEM graduate student instructors on proper laboratory techniques and safety procedures.

    Future Safety and Security Suggestions
    Since there was a Potential Risk that if released by accident, our parts and materials would do some negative damage to the general public. Our BioBrick parts or devices might raise the resistance of Escherichia coli to certain antibiotics. We suppose that we could design a mechanism into bacterium or add a device which can dissolve the released reagents.

    In addition, we believe that collecting the safety concerns and information into a biosafety criterion book and making it become one of the criteria would improve adherence to biosafety regulations.

    References
    [1]U.S Department of Health and Human Services, Biosafety in Microbiological and Biomedical Laboratories, Fifth Edition, US Government Printing Office, 2007

    [2]World Health Organization, Laboratory Biosafety Manual, Third Edition, 2004

    Retrieved from "http://2012.igem.org/Template:Team:XMU-China/safety"