Template:Team:XMU-China/safety

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<title>XMU-SAFETY</title>
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<p align="center" class="tit"><strong>SAFETY</strong></p>
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        <p align="center"><strong class="tit">SAFETY</strong></p>
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        <p><strong class="subtitle"><a name="Toc01" id="Toc01"></a>Researcher, Public and Environmental Safety </strong><br>
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          The genetic materials used in our project pose no safety or health concerns to members in the laboratory. There were certain chemicals and solvents we used in laboratory that are known to be toxic such as ethidium bromide, but all were treated with proper caution and care. We strictly followed the<strong> BSL-1</strong> requirements. All biological wastes and equipments that have physical contacts with biological samples were bleached that was optional and autoclaved before disposal and reuse. If released by accident, our parts and materials would do some negative damage to the general public. Our BioBrick parts or devices might raise the resistance of<em> <strong>Escherichia coli </strong></em>to certain antibiotics. As we were not conducting large-scale proliferation of microorganisms, the leakage of the bacteria cultured for testing experiments would not have significant impact on the general safety of the environment. However, we strictly followed the <strong>BSL-1</strong> requirements as mentioned above and avoided any release of the  BioBrick parts or devices or microorganisms to the environment. <strong> </strong></p>
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        <p align="left">The environment was also in no danger from such a hypothetical release for reasons stated previously. Also, model organisms used in our project included<strong><em> Escherichia coli</em> BL21 and DH5α</strong>.  They are non-virulent strains which are commonly used in microbiology  laboratories. </p>
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  <p><a href="#_Toc334813185"><strong>Researcher,  Public and Environmental Safety </strong></a> <br >
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        <p align="left">Besides, there would be no risks to security through malicious misuse by individuals, groups or states. Any malicious misuse of BioBrick parts or devices or microorganisms might have great threat to security. To avoid these potential hazards, we have carefully handled our experiments, stored our materials and products. Human error and poor technique could compromise the best of safeguards to protect the researcher and cause unpredicted risks to both human and environment. For this reason, we have conducted a continuous training in safety measures for all 2012 XMU-China team members and other laboratory workers in our laboratory.</p><hr>
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    <a href="#_Toc334813186"><strong>Biosafety  Standards and Institutions</strong>. </a> <br >
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        <p align="left"><strong class="subtitle"><a name="Toc02"></a>Biosafety Standards and Institutions</strong><br>
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    <a href="#_Toc334813187"><strong>Biosafety  Training</strong></a> <br >
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          Xiamen University has its own biosafety rules that are regulated by the Ministry of Environment Protection, P.R. China and our institution. We carried out our experiments and evaluated bio-safety issues in our iGEM project strictly according to the Chinese Pathogenic Microbiology Laboratory Bio-safety Regulations, 2004, P.R. China. </p>
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    <a href="#_Toc334813188"><strong>Future Safety and Security  Suggestions</strong></a></p>
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        <p>Link to the Nation Biosafety Office: <br>
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          <a href="http://english.biosafety.gov.cn/">National Biosafety Office</a><sup><a href="#_ENREF_1" title="Ron Weiss, 2003 #2">[1]</a></sup></p>
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<br>
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        <p>Link to the regulations: <br>
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          <a href="http://www1.www.gov.cn/zwgk/2005-05/23/content_256.htm">Biosafety regulation on pathogenic microbes</a> <sup><a href="#_ENREF_2" title="Ron Weiss, 2003 #2">[2]</a></sup><u> </u></p><hr>
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<p class="subtitle"><a name="_Toc334813185" id="_Toc334813185">Researcher, Public and Environmental Safety &shy;</a> </p>
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        <p><strong class="subtitle"><a name="Toc03"></a>Biosafety Training</strong><br>
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  <p>The genetic materials used in our project pose no safety or health concerns to members in the laboratory. There were certain chemicals and solvents we used in laboratory that are known to be toxic such as ethidium bromide, but all were treated with proper caution and care. We strictly followed the<strong> BSL-1</strong> requirements. All biological wastes and equipments that have physical contacts with biological samples were bleached that was optional and autoclaved before disposal and reuse. If released by accident, our parts and materials would do some negative damage to the general public. Our BioBrick parts or devices might raise the resistance of <strong>Escherichia coli</strong> to certain antibiotics. As we were not conducting large-scale proliferation of microorganisms, the leakage of the bacteria cultured for testing experiments would not have significant impact on the general safety of the environment. However, we strictly followed the <strong>BSL-1</strong> requirements as mentioned above and avoided any release of the BioBrick parts or devices or microorganisms to the environment. <br />
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          Every member of our laboratory received biosafety training before the project began. It included general laboratory safety, biosafety and hazardous and chemical spill training. These training sessions were put on by the code of practice and the local guidelines, and including the safety and operations manual as well. Furthermore, every member of the iGEM team was  trained by our iGEM graduate student instructors on proper laboratory techniques and safety procedures.</p><hr>
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  The environment was also in no danger from such a hypothetical release for reasons stated previously. Also, model organisms used in our project included<strong> </strong><strong>Escherichia coli</strong><strong> </strong><strong>BL21</strong><strong> and DH5</strong><strong>&alpha;</strong>.  They are non-virulent strains which are commonly used in microbiology  laboratories. <br />
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        <p><strong class="subtitle"><a name="Toc04"></a>Future Safety and Security Suggestions</strong><br>
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Besides, there would be no risks to security through malicious misuse by individuals, groups or states. Any malicious misuse of BioBrick parts or devices or microorganisms might have great threat to security. To avoid these potential hazards, we have carefully handled our experiments, stored our materials and products. Human error and poor technique could compromise the best of safeguards to protect the researcher and cause  unpredicted risks to both human and environment. For this reason, we have conducted a continuous training in safety measures for all 2012 XMU-China team members and other laboratory workers in our laboratory.</p><hr />
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          Since there was a <strong>Potential Risk </strong>that if released by accident, our parts and materials would do some negative damage to the general public. Our BioBrick parts or devices might raise the resistance of<em> <strong>Escherichia coli</strong></em> to certain antibiotics. We suppose that we could design a mechanism into bacterium or add a device which can dissolve the released reagents.</p>
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<p class="subtitle"><a name="_Toc334813186" id="_Toc334813186"></a>Biosafety Standards and Institutions</p> <p>
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        <p>In addition, we believe that collecting the safety concerns and information into a biosafety criterion book and making it become one of the  criteria would improve adherence to biosafety regulations.</p><hr>
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  Xiamen University has its own biosafety rules that are regulated by the Ministry of Environment Protection, P.R. China and our institution. We carried out our experiments and evaluated bio-safety issues in our iGEM project strictly according to the Chinese Pathogenic Microbiology Laboratory Bio-safety Regulations, 2004, P.R. China. <br />
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        <p><strong class="subtitle"><a name="Toc05"></a>References</strong><br>
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  Link to the Nation Biosafety Office: <br />
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          <a name="_ENREF_1" id="_ENREF_1">[1]U.S Department of Health and Human Services, Biosafety in  Microbiological and Biomedical Laboratories, Fifth Edition, US Government  Printing Office, <strong>2007</strong></a></p>
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  <a href="http://english.biosafety.gov.cn/" style="text-decoration:underline">National Biosafety Office</a><br />
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        <p><a name="_ENREF_2" id="_ENREF_2">[2]World Health Organization, Laboratory Biosafety Manual, Third Edition,  <strong>2004</strong></a></p>
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Link to the regulations: <br />
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      </div>
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<a href="http://www1.www.gov.cn/zwgk/2005-05/23/content_256.htm" style="text-decoration:underline">Biosafety regulation on pathogenic microbes</a></p>
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<hr />
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<p class="subtitle"><a name="_Toc334813187" id="_Toc334813187"></a><strong>Biosafety Training</strong> </p>
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Every member of our laboratory received biosafety training before the project began. It included general laboratory safety, biosafety and hazardous and chemical spill training. These training sessions were put on by the code of practice and the local guidelines, and including the safety and operations manual as well.&nbsp;  Furthermore, every member of the iGEM team was  trained by our iGEM graduate student instructors on proper laboratory techniques and safety procedures.</p><hr />
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<p class="subtitle"><a name="_Toc334813188" id="_Toc334813188"><strong>Future Safety and Security Suggestions</strong></a></p>
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  <p>Since there was a <strong>Potential Risk </strong>that if released by accident, our parts and materials would do some negative damage to the general public. Our BioBrick parts or devices might raise the resistance of <strong>Escherichia coli</strong> to certain antibiotics. We suppose that we could design a mechanism into bacterium or add a device which can dissolve the released reagents.&nbsp; <strong> </strong><br />
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&nbsp;In addition, we believe that collecting the safety concerns and information into a biosafety criterion book and making it become one of the  criteria would improve adherence to biosafety regulations.</p>
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Latest revision as of 02:00, 26 September 2012

XMU-CSS

XMU

safetyindex

Contents[hide][show]
  • Researcher, Public and Environmental Safety
  • Biosafety Standards and Institutions
    		•
  • Biosafety Training
  • Future Safety and Security Suggestions
    		•
  • References
    		•

    XMU-SAFETY

    SAFETY

    Researcher, Public and Environmental Safety
    The genetic materials used in our project pose no safety or health concerns to members in the laboratory. There were certain chemicals and solvents we used in laboratory that are known to be toxic such as ethidium bromide, but all were treated with proper caution and care. We strictly followed the BSL-1 requirements. All biological wastes and equipments that have physical contacts with biological samples were bleached that was optional and autoclaved before disposal and reuse. If released by accident, our parts and materials would do some negative damage to the general public. Our BioBrick parts or devices might raise the resistance of Escherichia coli to certain antibiotics. As we were not conducting large-scale proliferation of microorganisms, the leakage of the bacteria cultured for testing experiments would not have significant impact on the general safety of the environment. However, we strictly followed the BSL-1 requirements as mentioned above and avoided any release of the BioBrick parts or devices or microorganisms to the environment.

    The environment was also in no danger from such a hypothetical release for reasons stated previously. Also, model organisms used in our project included Escherichia coli BL21 and DH5α. They are non-virulent strains which are commonly used in microbiology laboratories.

    Besides, there would be no risks to security through malicious misuse by individuals, groups or states. Any malicious misuse of BioBrick parts or devices or microorganisms might have great threat to security. To avoid these potential hazards, we have carefully handled our experiments, stored our materials and products. Human error and poor technique could compromise the best of safeguards to protect the researcher and cause unpredicted risks to both human and environment. For this reason, we have conducted a continuous training in safety measures for all 2012 XMU-China team members and other laboratory workers in our laboratory.

    Biosafety Standards and Institutions
    Xiamen University has its own biosafety rules that are regulated by the Ministry of Environment Protection, P.R. China and our institution. We carried out our experiments and evaluated bio-safety issues in our iGEM project strictly according to the Chinese Pathogenic Microbiology Laboratory Bio-safety Regulations, 2004, P.R. China.

    Link to the Nation Biosafety Office:
    National Biosafety Office[1]

    Link to the regulations:
    Biosafety regulation on pathogenic microbes [2]

    Biosafety Training
    Every member of our laboratory received biosafety training before the project began. It included general laboratory safety, biosafety and hazardous and chemical spill training. These training sessions were put on by the code of practice and the local guidelines, and including the safety and operations manual as well. Furthermore, every member of the iGEM team was trained by our iGEM graduate student instructors on proper laboratory techniques and safety procedures.

    Future Safety and Security Suggestions
    Since there was a Potential Risk that if released by accident, our parts and materials would do some negative damage to the general public. Our BioBrick parts or devices might raise the resistance of Escherichia coli to certain antibiotics. We suppose that we could design a mechanism into bacterium or add a device which can dissolve the released reagents.

    In addition, we believe that collecting the safety concerns and information into a biosafety criterion book and making it become one of the criteria would improve adherence to biosafety regulations.

    References
    [1]U.S Department of Health and Human Services, Biosafety in Microbiological and Biomedical Laboratories, Fifth Edition, US Government Printing Office, 2007

    [2]World Health Organization, Laboratory Biosafety Manual, Third Edition, 2004

    Retrieved from "http://2012.igem.org/Template:Team:XMU-China/safety"