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Team:HIT-Harbin
From 2012.igem.org
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This is the oldest building of Harbin Institute of Technology
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The most famous street with historical buildings
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A visual description of the whole lab work we've done
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There is a tough problem need to be settled
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For the birthday celebration of our former team leader
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We have a wonderful experience in the lab this summer
We use engineered E. coli.to detect the existence of S.aureus in the environment through sensing the AIPs secreted only from S.aureus, and the report will be shown by the expression of GFP.
The construct is designed to eradicate S.aureus through the production of lysostaphin, which would be released till a certain concentration.
In order to increase bactericidal effect, we enhance biofilm formation by over-expression of yddV, a di-guanylate cyclase, which catalyzes GTP into c-di-GMP.
The system we have designed can be applied to the pools which contain flowing water with existence of S.aureus. For further application, this device can developed for medical use.
The HIT-Harbin team is composed of 15 motivated students across a wide range of academic backgrounds this year: from freshman to senior, from biology to electromechanics. The identical dream makes us together to share a passion for science, stay-up late in the lab and learn. We're currently taking great efforts to make it and enjoying the happiness and sadness it bring to us.
