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Team:Chalmers-Gothenburg/Theory
From 2012.igem.org
Introduction
In this section we present some information needed to understand the design of our biosensor. Firstly, a short introduction to G protein-coupled receptors will be given. Thereafter, the hCG hormone, its associated LH/CG receptor and their roles during pregnancy will be discussed. The construction of our hCG biosensor will require the assembly of several biological components in yeast, such as a functional human GPCR, a modified pheromone signaling pathway, and reporter genes encoding indigo-synthesizing enzymes. Hence, in this section, we will also present needed background information and previous approaches within these areas.
