Team:Arizona State/Magainin

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Magainin-Split Beta-Galactosidase Biosensor

Overview

Current methods of water-borne pathogen detection require expensive equipment that often isn't modular, high throughput, or accessible to developing countries. One of the projects this year's ASU iGEM undertook was building a split-enzyme engineered fusion protein consisting of the Magainin peptide and the split alpha and omega fragments of beta-galactosidase.

Magainin

Magainins are a class of proteins found in Xenopus laevis[http://en.wikipedia.org/wiki/Xenopus_laevis] - the African clawed frog - that contain antimicrobial properties.