Team:EPF-Lausanne/Modeling/Expression

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Revision as of 08:32, 26 September 2012 by Diego.marcos (Talk | contribs)

Why?

From our work on LOV2 photoactivation we might be able to predict the percentage of LOV2 domains in our LovTAP-VP16, even though this value might be affected by the fact of having both ends fused to other domains: TrpR and VP16.

EPF-Lausanne-Modeling-path simple.png

92% of photoactive LOV2 has it's Jα-helix undocked (Yao et al, 2008).

Eitoku et al (2005) say it takes 2 ms for the J&alpha-helix to undock.