Team:TU Darmstadt/Cooperation

From 2012.igem.org

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== Cooperation ==
== Cooperation ==
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Capacity for teamwork is one major feature and character of the [https://2012.igem.org/ iGEM competition]. Since we first met [https://2012.igem.org/Team:Frankfurt team frankfurt] at the [https://2012.igem.org/Team:TU_Darmstadt#06.2F22_Achema Achema] our paths crossed on several occasions. During these occasions we came up with the idea to give them support by modelling their enzymes. The simulations group performed modelling studies for the enzymes of Frankfurt iGEM Team as with our own. <br>
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Capacity for teamwork is one major feature and character of the [https://2012.igem.org/ iGEM competition]. Since we first met [https://2012.igem.org/Team:Frankfurt team frankfurt] at the [https://2012.igem.org/Team:TU_Darmstadt#06.2F22_Achema Achema] our paths crossed on several occasions. During these occasions we came up with the idea to give them support by modelling their enzymes. The simulations group performed modelling studies for three enzymes of the Frankfurt iGEM Team. <br>
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We were able to develop a homology model of their Saccharomyces FPP Synthase (SFPPS) as seen in the following pictures. <br><br>
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For the Saccharomyces HMG CoA Reductase and Sulfolobus GGPP Synthase we were not able to build homology models, but their Saccharomyces FPP Synthase (SFPPS) worked out. The results for the successful developed SFPPS and the two other enzymes can be seen in the following pictures. <br><br>
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File:FPP_Synthase2.png|[[Side view of SFPPS]]
File:FPP_Synthase2.png|[[Side view of SFPPS]]
File:FPP_Synthase3.png|[[Surface charge of SFPPS]]
File:FPP_Synthase3.png|[[Surface charge of SFPPS]]
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File:Sulfolobus_GGPP_Synthase.png|[[Aborted model of Sulfolobus GGPP Synthase]]
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File:Saccharomyces_HMG_CoA_Reduktase.png|[[Aborted model of Saccharomyces HMG CoA Reduktase]]
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Revision as of 17:02, 26 September 2012

Cooperation

Capacity for teamwork is one major feature and character of the iGEM competition. Since we first met team frankfurt at the Achema our paths crossed on several occasions. During these occasions we came up with the idea to give them support by modelling their enzymes. The simulations group performed modelling studies for three enzymes of the Frankfurt iGEM Team.
For the Saccharomyces HMG CoA Reductase and Sulfolobus GGPP Synthase we were not able to build homology models, but their Saccharomyces FPP Synthase (SFPPS) worked out. The results for the successful developed SFPPS and the two other enzymes can be seen in the following pictures.