Team:St Andrews/Human-practices

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Scientific impact of iGEM

"Most influential synthetic biology competition" vs. "Just some kids playing"?

We investigated the scientific attention garnered by iGEM and the Registry of Standard Parts. A data-driven approach was chosen: We extracted data from search results to various queries (such as ("iGEM" OR "International Genetically Engineered Machine") AND ("synthetic biology" OR "genetic engineering")) from various publication search engines. We searched Web of Knowledge, Scopus, PubMed and Google Scholar. Google Scholar was chosen due to the alternatives' various shortcomings.

We conclude with hypotheses to explain the results and discuss their implications for the iGEM competition.

TODO Put findings summary here too.

Why we used Google Scholar

We must admit iGEM is somewhat of a niche topic. WoK, Scopus and PubMed are strictly curated and limited in scope, so they missed many obviously relevant publications. We also found their search options unsuitable: Many of them did not support full text search (they looked at titles, keywords and abstracts only) or boolean operators. These were requirements, for the following reasons: iGEM cannot be expected to always be the main subject of a paper, hence full text search. There are many relevant terms floating about iGEM, hence boolean operators like "OR" to allow treating papers that contain "International Genetically Engineered Machine" or the acronym "iGEM" equally. Google Scholar, however, fulfilled these requirements.

What sort of scope range are we talking about here? Here is an example: PubMed gave so few results (16 for iGEM genetic*) that we quickly discarded it. Manually merging the Web of Knowledge and Scopus results for the query iGEM AND genetic* (discarding obviously irrelevant results) gave 43 results. Then we queried Google Scholar. It gave us 770 for (“synthetic biology” OR "genetic engineering") AND (“iGEM” OR “International Genetically Engineered Machine"). Imagine our expressions.

Of course, Google Scholar too is but a bronze bullet: It brings its own drawbacks. It is engineered to pick up things that only seem like scholarly articles. Like Google's search results in general, the results are not curated by a human. This has been criticised in the literature. Also we found the occasional hilarious total miss. Google Scholar is also known to somewhat overestimate citation counts. However, we concluded from empirical manual examination of a random sample that the majority of the results are plausible and (most importantly) far greater in scope than searches in curated databases. We only want statistics to identify trends. For this, large and coarce pieces suffice. We discourage using our method for obtaining precise values!

Browse the data

...are online in a nifty and very usable Google Docs folder.

An introduction is included in case you get lost or want more information.

On extraction tools

We made extensive use of Harzing Publish or Perish (TODO Cite as "Harzing, A.W. (2007) Publish or Perish, available from http://www.harzing.com/pop.htm"!) to scrape Google Scholar results. The tool has many limitations. However, it is in our experience the best out there for managing the mess that scientific publication data scraping tends to become!

We did try other things: We quickly found manual methods too slow. Various Firefox browser plugins simply failed outright, were extremely awkward to use or produced clearly erroneous results. The Mac OS program Papers was easy to use and found huge numbers of papers (as it could access many sources), but had unacceptably high rates of error, problems with duplicates and could not export the results into a form we could easily process. Hence Publish or Perish.

Query summary

Here's a quick breakdown of what we queried for on Google Scholar and what sort of data was returned.

Plain English query Query Nº Papers Nº Citations h-index g-index Query date
Papers mentioning iGEM iGEM OR "International Genetically Engineered Machine" 1000 9095 36 64 17/7/2012
Papers mentioning iGEM and Registry ("iGEM" OR "International Genetically Engineered Machine") AND("Registry of Standard Biological Parts" OR "partsregistry.org" OR "parts.mit.edu") 330 2208 23 42 17/7/2012
Papers mentioning iGEM in context of synbio (“synthetic biology” OR "genetic engineering") AND (“iGEM” OR “International Genetically Engineered Machine") 770 3253 26 45 17/7/2012
All synthetic biology synthetic biology 1000 68482 127 214 17/7/2012
Papers mentioning Registry of Parts "Registry of Standard Biological Parts" OR "partsregistry.org" OR "parts.mit.edu" 751 6442 39 69 17/7/2012
Papers citing a particular Part partsregistry.org/Part: 54 263 5 16 17/7/2012

Note Searches were capped at a maximum of 1000 results. Hence getting 1000 results for a query implies that more exist! Those first 1000 are only the ones the search engine judged most relevant.

There are many ways you could quantify success of a paper. Here are a few we investigated:

Plain citation count

It's good scientific practice to cite (to mention relevant publications in one's own paper). High citation count can hence generally be taken as an indicator of a high-quality or high-impact paper. This is the most traditional method of ranking the influence of papers.

The main disadvantage of the "citation count"-method is its non-universality. Even papers in distinct scientific fields have differing standards and counts of citations. It is also significant that old papers have an edge over newer papers, as they've had more time to be cited.

h-index

The h-index is an integer unique to a set of papers. It is used to measure the output and influence of a set of scientists. A greater h-index implies more productive and more influential authors. It was invented by physicist J.E. Hirsch in 2005 and has since been automatically calculated by many citation databases. Here is its definition: "A set of papers has h-index h if h papers out of that set have been cited at least h times." An image from Wikipedia clarifies:

g-index

The g-index is another citation index meant to quantify the influence of papers. It was proposed in 2006 by Leo Egghe as a variation to the h-index. It puts more emphasis on the most cited papers and Egghe argues that it ranks highly cited authors more fairly. He gives the following definition: "A set of papers has a g-index g if g is the highest rank such that the top g papers have, together, at least citations." Here's a Wikipedia-sourced diagrammatic explanation again (Thanks, user "Ael 2"!):

Algorithmic methods

It's worth noting that there are many other ways of quantifying productivity and impact of a set of papers or scientists. For example, Y.B. Zhou et al propose a more complete method for "distinguishing prestige from popularity". In their algorithm, the weight of a citation to the influence of a paper is also dependent on the (already calculated) influences of the citing papers and their authors. This requires running a recursive algorithm on sufficiently complete bipartite network of papers and their authors.

We've looked mainly at citation count, h-index and g-index. The algorithmic methods were beyond our reach due to unavailability of data: We would have had to find the names of everyone in every iGEM team and all papers they've written, filtering out large amounts of false matches. This was impracticable.

TODO Explain choices even better?

Is iGEM getting attention?

What's "attention"? We will operate on the axiom that getting attention correlates very strongly with being mentioned. With this assumption, the attention a term is getting is quantifiable simply by searching for that term and summing up result counts.

Here is a chart summarising how many papers mention various terms floating about iGEM over time:

Looking good!

TODO Commentate more.

Old data (in case it still becomes useful)

Authors Title Year Source title Cited by
Boyle P.M.; Burrill D.R.; Inniss M.C.; Agapakis C.M.; Deardon A.; DeWerd J.G.; Gedeon M.A.; Quinn J.Y.; Paull M.L.; Raman A.M.; Theilmann M.R.; Wang L.; Winn J.C.; Medvedik O.; Schellenberg K.; Haynes K.A.; Viel A.; Brenner T.J.; Church G.M.; Shah J.V.; Silver P.A. A BioBrick compatible strategy for genetic modification of plants 2012 Journal of Biological Engineering
Hesselman M.C.; Odoni D.I.; Ryback B.M.; de Groot S.; van Heck R.G.A.; Keijsers J.; Kolkman P.; Nieuwenhuijse D.; van Nuland Y.M.; Sebus E.; Spee R.; de Vries H.; Wapenaar M.T.; Ingham C.J.; Schroen K.; Martins dos Santos V.A.P.; Spaans S.K.; Hugenholtz F.; van Passel M.W.J. A multi-platform flow device for microbial (co-) cultivation and microscopic analysis 2012 PLoS ONE
Materi W. Leading a successful iGEM team 2012 Methods in Molecular Biology
Ho-Shing O.; Lau K.H.; Vernon W.; Eckdahl T.T.; Campbell A.M. Assembly of standardized DNA parts using biobrick ends in E. coli 2012 Methods in Molecular Biology
Giavitto J.-L. The modeling and the simulation of the fluid machines of synthetic biology 2012 Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Muller K.M.; Arndt K.M. Standardization in synthetic biology 2012 Methods in Molecular Biology
Kuldell N. Living machines: Some assembly required: Kit-based competitions challenge teams of students to learn microbiology and design principles in the context of synthetic biology 2012 Microbe
Stewart D.; Wilson-Kanamori J.R. Modular modelling in synthetic biology: Light-based communication in E. coli 2011 Electronic Notes in Theoretical Computer Science
Dixon J.; Kuldell N. BioBuilding: Using banana-scented bacteria to teach synthetic biology 2011 Methods in Enzymology 1
Mitchell R.; Dori Y.J.; Kuldell N.H. Experiential Engineering Through iGEM-An Undergraduate Summer Competition in Synthetic Biology 2011 Journal of Science Education and Technology
Dress L. iGEM 2010: Synthetic biologists compete for the future 2010 Industrial Biotechnology
Hafner S. IGEM 2009: Synthethic biology and ethics [Les iGEM 2009 la biologie synth-éthique] 2010 Medecine/Sciences 2
Gu X.; Trybilo M.; Ramsay S.; Jensen M.; Fulton R.; Rosser S.; Gilbert D. Engineering a novel self-powering electrochemical biosensor 2010 Systems and Synthetic Biology
Cai Y.; Wilson M.L.; Peccoud J. GenoCAD for iGEM: A grammatical approach to the design of standard-compliant constructs 2010 Nucleic Acids Research 12
Cooling M.T.; Rouilly V.; Misirli G.; Lawson J.; Yu T.; Hallinan J.; Wipat A. Standard virtual biological parts: A repository of modular modeling components for synthetic biology 2010 Bioinformatics 10
Smolke C.D. Building outside of the box: IGEM and the BioBricks Foundation 2009 Nature Biotechnology 15
Hafner S. iGEM competition 2008; two French teams! [Compétition iGEM 2008: Deux équipes françaises!] 2009 Medecine/Sciences 2
Jerala R. I like iGEM 2009 Scientist
Edwards C. The gene machines 2008 Engineering and Technology
Bikard D.; Kepes F. First French team success during iGEM Synthetic biology competition [Succès de la première équipe française lors de la compétition iGEM de biologie synthétique] 2008 Medecine/Sciences 6
Bachman R. An iGEM of an idea? [2] 2008 Scientist
Kaczkowski P. An iGEM of an idea? [1] 2008 Scientist
Goodman C. Engineering ingenuity at iGEM 2008 Nature Chemical Biology 16
Gallagher R. An iGEM of an idea 2007 Scientist 2
Brown J. The iGEM competition: Building with biology 2007 IET Synthetic Biology 7
Haynes K.A.; Broderick M.L.; Brown A.D.; Butner T.L.; Harden L.; Heard L.; Jessen E.; Malloy K.; Ogden B.; Rosemond S.; Simpson S.; Zwack E.; Campbell A.M.; Eckdahl T.; Heyer L.J.; Poet J.L. Computing with living hardware 2007 IET Synthetic Biology 2
Dabholkar S.; Thattai M. Brainstorming biology 2007 IET Synthetic Biology 1
Brown T.; Chang C.; Heinze B.; Hollinger P.; Kittleson J.; MacDow K.; Reavis D.; Curry J.; Riley M. Development of an inducible three colour bacterial water colour system 2007 IET Synthetic Biology 1
Rodrigo G.; Montagud A.; Aparici A.; Aroca M.C.; Baguena M.; Carrera J.; Edo C.; Fernandez-De-Cordoba P.; Ferrando A.; Fuertes G.; Gimenez D.; Mata C.; Medrano J.V.; Navarrete C.; Navarro E.; Salgado J.; Tortosa P.; Urchueguia J.; Jaramillo A. Vanillin cell sensor 2007 IET Synthetic Biology 1
Quiroz J.N.A.; Flores R.B.; Cisneros T.G.B.; Rosales I.Y.F.; Naranjo A.G.; Sanchez J.C.G.; Jimenez M.E.G.; Padilla R.E.G.; Baena A.J.L.; Hernandez P.A.L.; Padilla P.G.; Miller R.P.; Gaspar I.N.R.; Chico J.C.R.; Martinez A.R.; Romero J.P.; Arzate A.S.; Barradas J.S.A.; Diaz D.A.; Bracho A.B.; Benitez C.; Arteag C.I.F.; Quiroz F.H.; Martinez G.J.; Rabadan J.L.; Salvador M.C.O.; Longoria P.P.; Orozco R.P.; Corona F.R.; Majarrez E.S.; Hassan E.S.; Sanchez C.S.; Saldana U.V.; Segura P.B.Z. Biological implementation of algorithms and unconventional computing 2007 IET Synthetic Biology
King P.; Lavrovsky V.; Von Mammen S.; Jacob C. Teaching bacteria how to dance 2007 IET Synthetic Biology
Badalamenti J.P.; Weiss L.E.; Buckno C.J.; Richard T.L.; Weiss P.S.; Cirino P.C. Synthetic sports: A bacterial relay race 2007 IET Synthetic Biology 1
Lohmueller J.; Neretti N.; Hickey B.; Kaka A.; Gao A.; Lemon J.; Lattanzi V.; Goldstein P.; Tam L.-K.; Schmidt M.; Brodsky A.S.; Haberstroh K.; Morgan J.; Palmore T.; Wessel G.; Jaklenec A.; Urabe H.; Gagnon J.; Cumbers J. Progress toward construction and modelling of a tri-stable toggle switch in E. coli 2007 IET Synthetic Biology 2
Ravi M.; Ngeleka M.; Kim S.-H.; Gyles C.; Berthiaume F.; Mourez M.; Middleton D.; Simko E. Contribution of AIDA-I to the pathogenicity of a porcine diarrheagenic Escherichia coli and to intestinal colonization through biofilm formation in pigs 2007 Veterinary Microbiology 10
Authors Title Year Source title Cited by
Cooling, M. T.; Rouilly, V.; Misirli, G.; Lawson, J.; Yu, T.; Hallinan, J.; Wipat, A. Standard virtual biological parts: a repository of modular modeling components for synthetic biology 2010 BIOINFORMATICS Not collected
Mitchell, Rudolph; Dori, Yehudit Judy; Kuldell, Natalie H. Experiential Engineering Through iGEM-An Undergraduate Summer Competition in Synthetic Biology 2011 JOURNAL OF SCIENCE EDUCATION AND TECHNOLOGY Not collected
Haefner, Sophia iGEM competition 2008, two French teams! 2009 M S-MEDECINE SCIENCES Not collected
Bikard, David; Kepes, Francois First French team success during iGEM synthetic biology competition 2008 M S-MEDECINE SCIENCES Not collected
Hafner, Sophia [IGEM 2009: synthetic biology and ethics]. 2010 Medecine sciences : M/S Not collected
Dixon, James; Kuldell, Natalie BIOBUILDING: USING BANANA-SCENTED BACTERIA TO TEACH SYNTHETIC BIOLOGY 2011 METHODS IN ENZYMOLOGY, VOL 497: SYNTHETIC BIOLOGY, METHODS FOR PART/DEVICE CHARACTERIZATION AND CHASSIS ENGINEERING, PT A Not collected
Ho-Shing, Olivia; Lau, Kin H; Vernon, William; Eckdahl, Todd T; Campbell, A Malcolm Assembly of standardized DNA parts using BioBrick ends in E. coli. 2012 Methods in molecular biology (Clifton, N.J.) Not collected
Materi, Wayne Leading a successful iGEM team. 2012 Methods in molecular biology (Clifton, N.J.) Not collected
Muller, Kristian M; Arndt, Katja M Standardization in synthetic biology. 2012 Methods in molecular biology (Clifton, N.J.) Not collected
Smolke, Christina D. Building outside of the box: iGEM and the BioBricks Foundation 2009 NATURE BIOTECHNOLOGY Not collected
Goodman, Catherine Engineering ingenuity at iGEM 2008 NATURE CHEMICAL BIOLOGY Not collected
Cai, Yizhi; Wilson, Mandy L.; Peccoud, Jean GenoCAD for iGEM: a grammatical approach to the design of standard-compliant constructs 2010 NUCLEIC ACIDS RESEARCH Not collected
Hesselman, Matthijn C; Odoni, Dorett I; Ryback, Brendan M; de Groot, Suzette; van Heck, Ruben G A; Keijsers, Jaap; Kolkman, Pim; Nieuwenhuijse, David; van Nuland, Youri M; Sebus, Erik; Spee, Rob; de Vries, Hugo; Wapenaar, Marten T; Ingham, Colin J; Schroen, Karin; Martins Dos Santos, Vitor A P; Spaans, Sebastiaan K; Hugenholtz, Floor; van Passel, Mark W J A multi-platform flow device for microbial (co-) cultivation and microscopic analysis. 2012 PloS one Not collected
Vinson, Valda iGEM 2010 Jamboree 2010 SCIENCE Not collected
Jerala, Roman I like iGEM 2009 SCIENTIST Not collected
Bachman, Robert An iGEM of an idea? 2008 SCIENTIST Not collected
Kaczkowski, Peter An iGEM of an idea? 2008 SCIENTIST Not collected
Gallagher, Richard An iGEM of an Idea - How to get students to go into science 2007 SCIENTIST Not collected
Mueller, Kristian M.; Arndt, Katja M. Standardization in Synthetic Biology 2011 SYNTHETIC GENE NETWORKS: METHODS AND PROTOCOLS Not collected
Gu, X; Trybilo, M; Ramsay, S; Jensen, M; Fulton, R; Rosser, S; Gilbert, D Engineering a novel self-powering electrochemical biosensor. 2010 Systems and synthetic biology Not collected
Authors Title Year Source title Cited by
Anderson, J. Christopher, John Dueber, Mariana Leguia, Gabriel Wu, Jonathan Goler, Adam Arkin, and Jay Keasling. BglBricks: A Flexible Standard for Biological Part Assembly. 2010 Journal of Biological Engineering No data
Baumgardner, Jordan, Karen Acker, Oyinade Adefuye, Samuel Crowley, Will DeLoache, James Dickson, Lane Heard, et al. Solving a Hamiltonian Path Problem with a Bacterial Computer. 2009 Journal of Biological Engineering No data
Chen, Joanna, Douglas Densmore, Timothy Ham, Jay Keasling, and Nathan Hillson. DeviceEditor Visual Biological CAD Canvas. 2012 Journal of Biological Engineering No data
Hatch, Alex. Four Suggestions for Addressing Public Concern Regarding Synthetic Biology 2010 Journal of Biological Engineering No data
Haynes, Karmella, Marian Broderick, Adam Brown, Trevor Butner, James Dickson, W. Lance Harden, Lane Heard, et al. Engineering Bacteria to Solve the Burnt Pancake Problem. 2008 Journal of Biological Engineering No data
Kelly, Jason, Adam Rubin, Joseph Davis, Caroline Ajo-Franklin, John Cumbers, Michael Czar, Kim de Mora, Aaron Glieberman, Dileep Monie, and Drew Endy. Measuring the Activity of BioBrick Promoters Using an in Vivo Reference Standard. 2009 Journal of Biological Engineering No data
Kuldell, Natalie. Authentic Teaching and Learning Through Synthetic Biology. 2007 Journal of Biological Engineering No data
Norville, Julie, Ratmir Derda, Saurabh Gupta, Kelly Drinkwater, Angela Belcher, Andres Leschziner, and Thomas Knight. Introduction of Customized Inserts for Streamlined Assembly and Optimization of BioBrick Synthetic Genetic Circuits. 2010 Journal of Biological Engineering No data
Pasotti, Lorenzo, Susanna Zucca, Manuel Lupotto, Maria Cusella De Angelis, and Paolo Magni. Characterization of a Synthetic Bacterial Self-destruction Device for Programmed Cell Death and for Recombinant Proteins Release. 2011 Journal of Biological Engineering No data
Pearson, Brianna, Sam Snell, Kyri Bye-Nagel, Scott Tonidandel, Laurie Heyer, and A. Malcolm Campbell. Word Selection Affects Perceptions of Synthetic Biology. 2011 Journal of Biological Engineering No data
Shetty, Reshma, Drew Endy, and Thomas Knight. Engineering BioBrick Vectors from BioBrick Parts. 2008 Journal of Biological Engineering No data
Speer, Michael, and Tom Richard. Amplified Insert Assembly: An Optimized Approach to Standard Assembly of BioBrickTM Genetic Circuits. 2011 Journal of Biological Engineering No data
Authors Title Year Source title Cited by
J. Brown The iGEM competition: building with biology 2007 IET Synthetic Biology No data
P. King Teaching bacteria how to dance 2007 IET Synthetic Biology No data
J.P. Badalamenti Synthetic sports: a bacterial relay race 2007 IET Synthetic Biology No data
S. Dabholkar Brainstorming biology 2007 IET Synthetic Biology No data
T. Brown Development of an inducible three colour bacterial water colour system 2007 IET Synthetic Biology No data
J. Lohmueller Progress toward construction and modelling of a tri-stable toggle switch in E. coli 2007 IET Synthetic Biology No data
K.A. Haynes Computing with living hardware 2007 IET Synthetic Biology No data
J.N. Argota Quiróz Biological implementation of algorithms and unconventional computing 2007 IET Synthetic Biology No data
G. Rodrigo Vanillin cell sensor 2007 IET Synthetic Biology No data
Authors Title Year Source title Cited by
Kuldell, Natalie. Authentic Teaching and Learning Through Synthetic Biology. 2007 Journal of Biological Engineering No data
Haynes, Karmella, Marian Broderick, Adam Brown, Trevor Butner, James Dickson, W. Lance Harden, Lane Heard, et al. Engineering Bacteria to Solve the Burnt Pancake Problem. 2008 Journal of Biological Engineering No data
Shetty, Reshma, Drew Endy, and Thomas Knight. Engineering BioBrick Vectors from BioBrick Parts. 2008 Journal of Biological Engineering No data
Baumgardner, Jordan, Karen Acker, Oyinade Adefuye, Samuel Crowley, Will DeLoache, James Dickson, Lane Heard, et al. Solving a Hamiltonian Path Problem with a Bacterial Computer. 2009 Journal of Biological Engineering No data
Kelly, Jason, Adam Rubin, Joseph Davis, Caroline Ajo-Franklin, John Cumbers, Michael Czar, Kim de Mora, Aaron Glieberman, Dileep Monie, and Drew Endy. Measuring the Activity of BioBrick Promoters Using an in Vivo Reference Standard. 2009 Journal of Biological Engineering No data
Anderson, J. Christopher, John Dueber, Mariana Leguia, Gabriel Wu, Jonathan Goler, Adam Arkin, and Jay Keasling. BglBricks: A Flexible Standard for Biological Part Assembly. 2010 Journal of Biological Engineering No data
Hatch, Alex. Four Suggestions for Addressing Public Concern Regarding Synthetic Biology 2010 Journal of Biological Engineering No data
Norville, Julie, Ratmir Derda, Saurabh Gupta, Kelly Drinkwater, Angela Belcher, Andres Leschziner, and Thomas Knight. Introduction of Customized Inserts for Streamlined Assembly and Optimization of BioBrick Synthetic Genetic Circuits. 2010 Journal of Biological Engineering No data
Pasotti, Lorenzo, Susanna Zucca, Manuel Lupotto, Maria Cusella De Angelis, and Paolo Magni. Characterization of a Synthetic Bacterial Self-destruction Device for Programmed Cell Death and for Recombinant Proteins Release. 2011 Journal of Biological Engineering No data
Pearson, Brianna, Sam Snell, Kyri Bye-Nagel, Scott Tonidandel, Laurie Heyer, and A. Malcolm Campbell. Word Selection Affects Perceptions of Synthetic Biology. 2011 Journal of Biological Engineering No data
Speer, Michael, and Tom Richard. Amplified Insert Assembly: An Optimized Approach to Standard Assembly of BioBrickTM Genetic Circuits. 2011 Journal of Biological Engineering No data
Chen, Joanna, Douglas Densmore, Timothy Ham, Jay Keasling, and Nathan Hillson. DeviceEditor Visual Biological CAD Canvas. 2012 Journal of Biological Engineering No data
Vinson, Valda iGEM 2010 Jamboree 2010 SCIENCE Not collected
Goodman C. Engineering ingenuity at iGEM 2008 Nature Chemical Biology 16
Smolke C.D. Building outside of the box: IGEM and the BioBricks Foundation 2009 Nature Biotechnology 15
Cai Y., Wilson M.L., Peccoud J. GenoCAD for iGEM: A grammatical approach to the design of standard-compliant constructs 2010 Nucleic Acids Research 12
Ravi M., Ngeleka M., Kim S.-H., Gyles C., Berthiaume F., Mourez M., Middleton D., Simko E. Contribution of AIDA-I to the pathogenicity of a porcine diarrheagenic Escherichia coli and to intestinal colonization through biofilm formation in pigs 2007 Veterinary Microbiology 10
Cooling M.T., Rouilly V., Misirli G., Lawson J., Yu T., Hallinan J., Wipat A. Standard virtual biological parts: A repository of modular modeling components for synthetic biology 2010 Bioinformatics 10
Brown J. The iGEM competition: Building with biology 2007 IET Synthetic Biology 7
Bikard D., Kepes F. First French team success during iGEM Synthetic biology competition [Succès de la première équipe française lors de la compétition iGEM de biologie synthétique] 2008 Medecine/Sciences 6
Gallagher R. An iGEM of an idea 2007 Scientist 2
Haynes K.A., Broderick M.L., Brown A.D., Butner T.L., Harden L., Heard L., Jessen E., Malloy K., Ogden B., Rosemond S., Simpson S., Zwack E., Campbell A.M., Eckdahl T., Heyer L.J., Poet J.L. Computing with living hardware 2007 IET Synthetic Biology 2
Lohmueller J., Neretti N., Hickey B., Kaka A., Gao A., Lemon J., Lattanzi V., Goldstein P., Tam L.-K., Schmidt M., Brodsky A.S., Haberstroh K., Morgan J., Palmore T., Wessel G., Jaklenec A., Urabe H., Gagnon J., Cumbers J. Progress toward construction and modelling of a tri-stable toggle switch in E. coli 2007 IET Synthetic Biology 2
Hafner S. iGEM competition 2008, two French teams! [Compétition iGEM 2008: Deux équipes françaises!] 2009 Medecine/Sciences 2
Hafner S. IGEM 2009: Synthethic biology and ethics [Les iGEM 2009 la biologie synth-éthique] 2010 Medecine/Sciences 2
Dabholkar S., Thattai M. Brainstorming biology 2007 IET Synthetic Biology 1
Brown T., Chang C., Heinze B., Hollinger P., Kittleson J., MacDow K., Reavis D., Curry J., Riley M. Development of an inducible three colour bacterial water colour system 2007 IET Synthetic Biology 1
Rodrigo G., Montagud A., Aparici A., Aroca M.C., Baguena M., Carrera J., Edo C., Fernandez-De-Cordoba P., Ferrando A., Fuertes G., Gimenez D., Mata C., Medrano J.V., Navarrete C., Navarro E., Salgado J., Tortosa P., Urchueguia J., Jaramillo A. Vanillin cell sensor 2007 IET Synthetic Biology 1
Badalamenti J.P., Weiss L.E., Buckno C.J., Richard T.L., Weiss P.S., Cirino P.C. Synthetic sports: A bacterial relay race 2007 IET Synthetic Biology 1
Dixon J., Kuldell N. BioBuilding: Using banana-scented bacteria to teach synthetic biology 2011 Methods in Enzymology 1
Quiroz J.N.A., Flores R.B., Cisneros T.G.B., Rosales I.Y.F., Naranjo A.G., Sanchez J.C.G., Jimenez M.E.G., Padilla R.E.G., Baena A.J.L., Hernandez P.A.L., Padilla P.G., Miller R.P., Gaspar I.N.R., Chico J.C.R., Martinez A.R., Romero J.P., Arzate A.S., Barradas J.S.A., Diaz D.A., Bracho A.B., Benitez C., Arteag C.I.F., Quiroz F.H., Martinez G.J., Rabadan J.L., Salvador M.C.O., Longoria P.P., Orozco R.P., Corona F.R., Majarrez E.S., Hassan E.S., Sanchez C.S., Saldana U.V., Segura P.B.Z. Biological implementation of algorithms and unconventional computing 2007 IET Synthetic Biology 0
King P., Lavrovsky V., Von Mammen S., Jacob C. Teaching bacteria how to dance 2007 IET Synthetic Biology 0
Edwards C. The gene machines 2008 Engineering and Technology 0
Bachman R. An iGEM of an idea? [2] 2008 Scientist 0
Kaczkowski P. An iGEM of an idea? [1] 2008 Scientist 0
Jerala R. I like iGEM 2009 Scientist 0
Dress L. iGEM 2010: Synthetic biologists compete for the future 2010 Industrial Biotechnology 0
Gu X., Trybilo M., Ramsay S., Jensen M., Fulton R., Rosser S., Gilbert D. Engineering a novel self-powering electrochemical biosensor 2010 Systems and Synthetic Biology 0
Stewart D., Wilson-Kanamori J.R. Modular modelling in synthetic biology: Light-based communication in E. coli 2011 Electronic Notes in Theoretical Computer Science 0
Mitchell R., Dori Y.J., Kuldell N.H. Experiential Engineering Through iGEM-An Undergraduate Summer Competition in Synthetic Biology 2011 Journal of Science Education and Technology 0
Boyle P.M., Burrill D.R., Inniss M.C., Agapakis C.M., Deardon A., DeWerd J.G., Gedeon M.A., Quinn J.Y., Paull M.L., Raman A.M., Theilmann M.R., Wang L., Winn J.C., Medvedik O., Schellenberg K., Haynes K.A., Viel A., Brenner T.J., Church G.M., Shah J.V., Silver P.A. A BioBrick compatible strategy for genetic modification of plants 2012 Journal of Biological Engineering 0
Hesselman M.C., Odoni D.I., Ryback B.M., de Groot S., van Heck R.G.A., Keijsers J., Kolkman P., Nieuwenhuijse D., van Nuland Y.M., Sebus E., Spee R., de Vries H., Wapenaar M.T., Ingham C.J., Schroen K., Martins dos Santos V.A.P., Spaans S.K., Hugenholtz F., van Passel M.W.J. A multi-platform flow device for microbial (co-) cultivation and microscopic analysis 2012 PLoS ONE 0
Materi W. Leading a successful iGEM team 2012 Methods in Molecular Biology 0
Ho-Shing O., Lau K.H., Vernon W., Eckdahl T.T., Campbell A.M. Assembly of standardized DNA parts using biobrick ends in E. coli 2012 Methods in Molecular Biology 0
Giavitto J.-L. The modeling and the simulation of the fluid machines of synthetic biology 2012 Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 0
Muller K.M., Arndt K.M. Standardization in synthetic biology 2012 Methods in Molecular Biology 0
Kuldell N. Living machines: Some assembly required: Kit-based competitions challenge teams of students to learn microbiology and design principles in the context of synthetic biology 2012 Microbe 0

Graphs (currently nonsense test data)

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University of St Andrews, 2012.

Contact us: igem2012@st-andrews.ac.uk, Twitter, Facebook

This iGEM team has been funded by the MSD Scottish Life Sciences Fund. The opinions expressed by this iGEM team are those of the team members and do not necessarily represent those of Merck Sharp & Dohme Limited, nor its Affiliates.