Team:St Andrews

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     <title>StA iGEM Wiki 2012 - Home</title>
     <title>StA iGEM Wiki 2012 - Home</title>
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  <h4 class="alert-heading">Warning!</h4>
 
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  This website is under construction. Come back in the autumn to see the final result.
 
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<br><br>This is our week 3 out of 10.
 
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This is our week 3 out of 10.
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                 <h1>St Andrews iGEM 2012</h1>
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                 <p>University of St Andrews' team for 2012 <em>International Genetically Engineered Machine competition</em></p>
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                 <p>University of St Andrews team for the 2012 <em>International Genetically Engineered Machine competition</em></p>
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<p>Alternative omega-3 production and novel metal recovery methods</p>
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             <div class="span2"><img src="https://static.igem.org/mediawiki/2012/a/ad/Crest.gif" alt="University of St Andrews coat of arms"></div>
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                <h1>Metal binding protein</h1>
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<h1><a href="https://2012.igem.org/Team:St_Andrews/metal-binding">Metal binding protein</a></h1>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925002”><span class="badge">BBa_K925002</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925004”><span class="badge">BBa_K925004</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925005”><span class="badge">BBa_K925005</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925006”><span class="badge">BBa_K925006</span></a></button>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925007”><span class="badge">BBa_K925007</span></a></button>
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<img src="https://static.igem.org/mediawiki/2012/9/9f/MetalBindingLogo_100.png" align="left" />               
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<p>Precious and toxic metals from car catalysts frequently find their way into the
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environment. By developing metal-binding proteins, we can reverse metal aggregation on our roads. This not only reduces the environmental impact of personal transportation, but will proffer a new man-made mine of precious metals.</p>
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                <p>Precious metals are used in the manufacture of many modern products (laptops, headphones, even toasters), but their scarcity has lead to increased prices and in extreme cases, even polical conflict. [TODO CITE!]
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</p><p>A major reason for the impending shortage is the lack of recycling of these metals. It may be surprising to hear, for example, that some platinum used in minimal amounts in the manufacture of car tyres ends up in road dust. No attempts have been made to reclaim it from these unusual deposits. We envision microscopic engineered bacteria that reclaim microscopic fragments of metals that would otherwise be wasted.</p>
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                <p><a class="btn btn-large" href="https://2012.igem.org/Team:St_Andrews/metal-binding">Learn more</a></p>
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                <h1></h1>
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<h1><a href="https://2012.igem.org/Team:St_Andrews/Omega-3-synthesis">ω−3 fatty acids synthesis</a></h1>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925000”><span class="badge">BBa_K925000</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925001”><span class="badge">BBa_K925001</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925003”><span class="badge">BBa_K925003</span></a>
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<img src="https://static.igem.org/mediawiki/2012/5/57/OmegaThreeLogo_100.png" align="left" />               
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          <p>ω-3 fatty acid is a key component of the healthy human diet. The nutrient is only synthesized naturally in a handful of organisms (algae and oil-rich plants). Our team partially recreated the pathway for ω-3 production in <i>E. coli</i> using genes from the cyanobacteria <i>Synechocystis</i>, despite the difficulty of working with membrane-bound proteins. Until now, synthetic ω-3 production has only been achieved in plants. 
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                <h1>ω−3 fatty acids synthesis</h1>
 
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                <p>Omega-3 fatty acids are a chemical essential for human health. Fish are overwhelmingly the most efficient source of omega-3 fatty acids. However, the world's oceans are severely overexploited [TODO CITE!]. An alternative good source of omega-3 fatty acids would help alleviate this problem of overfishing.
 
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</p><p>We investigate the feasibility of genetically engineering the biological omega-3 synthesis pathway into bacteria. Thanks to the universality of genetic code, the knowledge we gain can also be applied to enable other organisms to produce this essential but scarce nutrient.
 
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                <p><a class="btn btn-large">Learn more</a></p>
 
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                <h1>Scientific impact of iGEM</h1>
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<h1><a href="https://2012.igem.org/Team:St_Andrews/Human-practices">Scientific impact of iGEM</a></h1>
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<img src="https://static.igem.org/mediawiki/2012/a/ac/ImpactLogo_100.png" align="left" />
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<p></p>
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                 <p>We investigate the relationship between the iGEM competition and the rest of the scientific community. Is iGEM <em>really</em> having scientific impact? How often, how fairly and by whom are iGEM teams cited? Does the iGEM competition result in scholarly articles being published? What can guarantee continued recognition within the SynBio community?</p>
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                <p><a class="btn btn-large">Learn more</a></p>
 
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<h1><a href="https://2012.igem.org/Team:St_Andrews/Modelling">The mathematics of ω-3</a></h1>
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                 <h1>Modeling ω−3 depletion scenarios</h1>
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                 <p>We modelled fish population dynamics. Our result: if we continue fishing in the current manner, by 2100, only a fraction of present day biomass will remain.  Yet, there is hope.  Indeed, realizing Team St Andrews' alternative production of omega-3 could be the measure necessary to save our seas.  We investigated the effect that alternative production can have on future fish biomass, as well as the practicalities of preserving life in this manner.</p>
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                         <li class="span3"><a href="http://www.lgcstandards.com/" class="thumbnail"><img src="http://dl.dropbox.com/u/491730/iGEm/images/sponsors/LGC.jpg" alt=""></a></li>
                         <li class="span3"><a href="http://www.lgcstandards.com/" class="thumbnail"><img src="http://dl.dropbox.com/u/491730/iGEm/images/sponsors/LGC.jpg" alt=""></a></li>
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                        <li class="span3"><a href="http://www.msd-uk.com/" class="thumbnail"><img src="https://static.igem.org/mediawiki/2012/b/b7/Msd.png" alt=""></a></li>
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                     <h1>iGEM</h1>
                     <h1>iGEM</h1>
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                     <p>The International Genetically Engineered Machine competition (iGEM) is the premiere undergraduate Synthetic Biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.</p>
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                     <p>The International Genetically Engineered Machine competition (iGEM) is the premier undergraduate synthetic biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.</p>
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<h4 class="alert-heading">Offline project summaries</h4>
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{{:Team:St_Andrews/Template:Footer}}

Latest revision as of 02:02, 23 October 2012

St Andrews iGEM '12

StA iGEM Wiki 2012 - Home

source

University of St Andrews' team for 2012 International Genetically Engineered Machine competition

Alternative omega-3 production and novel metal recovery methods

University of St Andrews coat of arms

Metal binding protein

BBa_K925002 BBa_K925004 BBa_K925005 BBa_K925006 BBa_K925007

Precious and toxic metals from car catalysts frequently find their way into the environment. By developing metal-binding proteins, we can reverse metal aggregation on our roads. This not only reduces the environmental impact of personal transportation, but will proffer a new man-made mine of precious metals.

ω−3 fatty acids synthesis

BBa_K925000 BBa_K925001 BBa_K925003

ω-3 fatty acid is a key component of the healthy human diet. The nutrient is only synthesized naturally in a handful of organisms (algae and oil-rich plants). Our team partially recreated the pathway for ω-3 production in E. coli using genes from the cyanobacteria Synechocystis, despite the difficulty of working with membrane-bound proteins. Until now, synthetic ω-3 production has only been achieved in plants.


Scientific impact of iGEM

We investigate the relationship between the iGEM competition and the rest of the scientific community. Is iGEM really having scientific impact? How often, how fairly and by whom are iGEM teams cited? Does the iGEM competition result in scholarly articles being published? What can guarantee continued recognition within the SynBio community?


The mathematics of ω-3

We modelled fish population dynamics. Our result: if we continue fishing in the current manner, by 2100, only a fraction of present day biomass will remain. Yet, there is hope. Indeed, realizing Team St Andrews' alternative production of omega-3 could be the measure necessary to save our seas. We investigated the effect that alternative production can have on future fish biomass, as well as the practicalities of preserving life in this manner.

Sponsors

iGEM

The International Genetically Engineered Machine competition (iGEM) is the premier undergraduate synthetic biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.

×

Offline project summaries

These are the downloadable versions of our project summaries:

Twitter


Back to top

University of St Andrews, 2012.

Contact us: igem2012@st-andrews.ac.uk, Twitter, Facebook

This iGEM team has been funded by the MSD Scottish Life Sciences Fund. The opinions expressed by this iGEM team are those of the team members and do not necessarily represent those of Merck Sharp & Dohme Limited, nor its Affiliates.

Retrieved from "http://2012.igem.org/Team:St_Andrews"