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Team:Evry/Project
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<h2><a name="human" style="text-decoration:none; color: white;"><b>Human practice:</b> What does it imply to engineer a pluri-cellular organism</a></h2> | <h2><a name="human" style="text-decoration:none; color: white;"><b>Human practice:</b> What does it imply to engineer a pluri-cellular organism</a></h2> | ||
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| + | <p>Working with vertebrates raises many ethical questions. We decided to track the changes in our attitude to animal experimentation during our project. Before starting our experiments, we answered a list of questions concerning the ethical aspects of our project. Our answers were based on a theoretical perspective, because most of us have never worked with live multicellular organisms before. We will continue our survey and observe the changes in our attitude with the advancement of our project. Because we are a multinational team, we are also interested in comparing animal rights in different parts of the world. </p> | ||
<p><a href="https://2012.igem.org/Team:Evry/HumanPractice">Go and visit the project page ></a></p> | <p><a href="https://2012.igem.org/Team:Evry/HumanPractice">Go and visit the project page ></a></p> | ||
Revision as of 15:24, 15 July 2012
Project overview
For our first participation in iGEM, we have decided to combine the future and the past, tradition with modernity and our project aims to combine Synthetic biology and the roots of french society: frogs. We will bring Xenopus, a model organism in developmental biology, to iGEM for the first time. We hope to show it can be a great multicellular chassis for the iGEM community. We will create tools for the next generation of iGEMers to be able to easily express synthetic systems in various tissues. In order to link all these parts together, we want to create an orthogonal, synthetic hormonal system using the plant hormone auxin, in order for the different tissues to communicate with one another.
A quick summary of each project is proposed in this page. Please go on the specific page of each project for more details!
The French Froggies: Engineering a new hormonal system in tadpoles
Xenopus is a model organism for develpmental biology, and Xenopus larvae are used as biosensors of water pollutants. Our aim is to pave the way towards integrated multicellular genetic circuits by creating a synthetic, orthogonal hormonal system. We want to use the plant hormone auxin for communication between organs, which would allow the creation of more advanced biosensors.
The us of a higher organism as a biosensor allows more meaningful measures of the dangers to humans than can be obtained with unicellular organisms. Furthermore, the use of a multicellular organism provides an additional level of complexity compared to single-celled organisms which multiplies the potential applications in terms of synthetic biology.
Go and visit the project page >
Modeling a tadpole: a multi-level approach
Go and visit the project page >
Biotic games: Better understanding of tadpole behavior through gaming
Go and visit the project page >
Goldenbrick: Using type 2S restriction enzymes for biobricks
Go and visit the project page >
Human practice: What does it imply to engineer a pluri-cellular organism
Working with vertebrates raises many ethical questions. We decided to track the changes in our attitude to animal experimentation during our project. Before starting our experiments, we answered a list of questions concerning the ethical aspects of our project. Our answers were based on a theoretical perspective, because most of us have never worked with live multicellular organisms before. We will continue our survey and observe the changes in our attitude with the advancement of our project. Because we are a multinational team, we are also interested in comparing animal rights in different parts of the world.
