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From 2012.igem.org

The French froggies: an artificial hormonal system in tadpoles

Establishment of a new chassis

The first objective of this project is to establish the fundamentals of synthetic biology for the Xenopus. Our project is the first in the iGEM competition working on a multicellular organism: the future of synthetic biology ?!

This is to develop and characterize a library of "brick" elements (promoters,rapporteurs, genes, tissue specific expression etc..) that will be formatted with "BioBriques" for integration the Registry of Standard Biological Parts.
This allows direct reuse of our results by students in future editions of iGEM, and by research teams worldwide.

Auxin as a new hormonal system in Xenopus

An inter tissues communication

Auxin Inductible Degron system

Biosensors

We will then create the "biosensors" and "biomonitors", capable of detecting pollutants in water by human societies. Its metabolism is similar to humans, but with a shorter life cycle, it is more readily possible to evaluate the impact of these molecules in animals and human beings who consume the contaminated water.