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Team:Penn State/Bidirectional Promoters Results
From 2012.igem.org
Team Projects
Utilizing synthetic biology cloning techniques, the Penn State iGEM team has designed three genetic constructs that test the most basic assumptions of molecular biology. While each of the individual projects looks at a different aspect of the mantra, they all come together under the umbrella of Questioning the Central Dogma of Molecular Biology.
Multiple Start Codons
mRNA strands should have only one recognized start codon. What happens when multiple start codons are introduced in translation?
Bidirectional Promoters
Promoters usually initiate translation in one direction. Which promoters promote both foward and reverse on the mRNA strand?
Codon Optimization
Each organism has a preferred sequence for each amino acid. What happens when the cell is overloaded by one amino acid codon?
