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Team:SUSTC-Shenzhen-B/before.june
From 2012.igem.org
Week 1
It is important that transcription is imperfectly terminated at some terminators so that the ratio of the amount of mRNA transcribed from upstream and that from downstream of the terminator is controlled. This is qualified as terminator efficiency.
We studied the Transcription Terminators which regulate the gene expression. We have developed a free energy based theoretical model to calculate the terminator efficiency from nucleotide sequences. Then, we did some experiment and measured the efficiency of more than 100 terminators to validate our model. Our work is by far the most comprehensive study on terminator efficiency.
This is the main page of our wiki. If you want to know more about our project please see detailed parts. Have a nice time!
Team Abstract
Our team consists of 7members, who are all sophomores of South University of Science and Technology of China. We are receiving the general education and don’t have our own major now, We gather because of the same hope, the unity.
MoreHuman Practice
Human practice is one of the IGEM activities that promote public awareness and education of synthetic biology and genetic engineering. As one of the IGEM team, we should contribute our share to the historic events----synthetic biology.
MoreHave a Try!
This is the address of our “transcriptional terminator efficiency calculator” website. Please input the terminator sequence and then choose an algorithm. When you press the button down it can predict the terminator efficiency and structure.
acknowledgements
This is the first time that we join this competition, we got many help from some companies and other teams. thanks for their help and supports!
