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Team:Wageningen UR/Modeling
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Modelling
Introduction
Modelling can be the final application, which could be modelling the VLP dose in case of drug delivery. A second possibility is predicting the folding of VLPs. It is known that the modification of a monomer influences the folding of the total VLP. Looking at the loops of the Hepatitis B VLP, this makes sense. Theses loops would be the primary target for modification, but are paired in the VLP structure. So, if the loops of both monomers are modified, it is very likely that the modification will interfere with the VLP formation.
