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Team:Tuebingen/Project
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Our aim is the expression of zebrafish (''Danio rerio'') membrane progestin receptor (mPR) in yeast to reliably measure steroid concentrations in water by inducing bioluminiscence. | Our aim is the expression of zebrafish (''Danio rerio'') membrane progestin receptor (mPR) in yeast to reliably measure steroid concentrations in water by inducing bioluminiscence. | ||
| - | === The problem: Effects of hormones on fish developement === | + | === Endocrine disruption in the aquatic environment === |
| + | Intersex fish have first been reported in UK rivers in 1978 just downstream of an sewage treatment plant (STP). Especially male young fish developed female sex tissue, so called ovotesties. What could have caused this unnatural occurrence? | ||
| + | <!--=== The problem: Effects of hormones on fish developement === | ||
| - | In the last years higher and higher concentrations of syntethic hormones have been measured in most of US rivers, disturbing not only gonad differentiation of juvenile fish, but also causing the developement of female sex tissue in male fish. The resulting high number of female fish decreases population size dramatically. | + | In the last years higher and higher concentrations of syntethic hormones have been measured in most of US rivers, disturbing not only gonad differentiation of juvenile fish, but also causing the developement of female sex tissue in male fish. The resulting high number of female fish decreases population size dramatically.--> |
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=== Experiments === | === Experiments === | ||
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Revision as of 12:04, 15 May 2012
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Overall project
Our aim is the expression of zebrafish (Danio rerio) membrane progestin receptor (mPR) in yeast to reliably measure steroid concentrations in water by inducing bioluminiscence.
Endocrine disruption in the aquatic environment
Intersex fish have first been reported in UK rivers in 1978 just downstream of an sewage treatment plant (STP). Especially male young fish developed female sex tissue, so called ovotesties. What could have caused this unnatural occurrence?
