Team:TU Darmstadt/Cooperation

Cooperation

Capacity for teamwork is one major feature and character of the iGEM competition. Since we first met team frankfurt at the Achema our paths crossed on several occasions. During these occasions we came up with the idea to give them support by modelling their enzymes. The simulations group performed modelling studies for three enzymes of the Frankfurt iGEM Team.
For the Saccharomyces HMG CoA Reductase and Sulfolobus GGPP Synthase we were not able to build homology models, but their Saccharomyces FPP Synthase (SFPPS) worked out. The results for the successful developed SFPPS and the two other enzymes can be seen in the following pictures.

FPP Synthase move klein.gif Animation of SFPPS	Top view of SFPPS
Side view of SFPPS	Surface charge of SFPPS

Aborted model of Sulfolobus GGPP Synthase

Aborted model of Saccharomyces HMG CoA Reduktase

File:Sulfolobus_GGPP_Synthase.png# File:Saccharomyces_HMG_CoA_Reduktase.png