Team:BAU-Indonesia/Attributions

From 2012.igem.org

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<h2><b>Safety</b></h2>
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<h2><b>Sponsorship Team Journey</b></h2>
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<div class="text"><br>                                     
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  <h3>
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  <h4><strong>09-15 Mei 2012</strong></h4>
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    <strong>1. Would any of your project ideas raise safety issues in
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    <h4>• Making the team delegate proposal: to be given to the High Education Office (the proposal has not been signed by the vice chancellor of academic and student affairs).<br> </h4>
     
     
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    terms of:
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  <h4><strong>20 Juni 2012</strong></h4>
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    <h4>• Sending proposals and cover letters  into High Education Office (the proposal has not been signed by the vice chancellor of academic and student affairs).<br> </h4>
                                          
                                          
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                                        </strong>
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                                        <h4><strong>24 Juni 2012</strong></h4>
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  </h3><br>                                     
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    <h4>• Making sponsorship proposal.<br> </h4>
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  <h4><strong>Researcher Safety</strong><br></h4>
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    <h4>We have isolated and cultured the bacteria sample from landfill
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                                        <h4><strong>23 Agustus 2012</strong></h4>
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    <h4>• Sending proposal to BRI and BNI (Bank), The proposal has not been signed by the vice chancellor of academic and student affairs. <br> </h4>
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    at Galuga, West Java Indonesia. To prevent contamination by some
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    harmfull bacteria, we have followed the instruction of safety
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                                        <h4><strong>3 September 2012</strong></h4>
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    <h4>• Following up proposal to the High Education Office. We got advice from the High Education Office to complete the proposal with the signature of vice chancellor of academic and student affairs. Our proposal to the BRI Bank had been rejected.<br> </h4>
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    procedure, such as using sensigloves, mask, and washing hand
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    after sampling. Hazardous chemicals that we used are aclrilamide
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                                        <h4><strong>6 September 2012</strong></h4>
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    <h4>• Following up to the bank (BRI & BNI), High Education Office. The proposal was still processed at BNI and BRI Bank. The proposal at High Education Office had been arrived at Public Division. <br> </h4>
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    and ethidium bromyde. Acrylamide (or acrylic amide) is a simple
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    organic compound with the chemical formula C3H5NO. It's
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                                        <h4><strong>11 September 2012</strong></h4>
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    potentially hazardous to health (cancer or carcinogenic).
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    <h4>• Making the new proposal and cover letters ( it has been signed by the Advisor, Dekan FMIPA The vice chancellor of academic and student affairs, Head of Department Biology)<br> </h4>
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    Acrylamide can form long polymer chains known as polyacrylamide,
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                                        <h4><strong>13 September 2012</strong></h4>
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    <h4>• Sending new proposal to the Bank (Mandiri & BNI), Indonesia State Gas Company,  The Ministry of Environment. The proposal has been completed by the cover letters from Bogor Agricultural University.<br> </h4>
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    which is also carcinogenic. Inhalation: irritation,
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                                        <h4><strong>24 September 2012</strong></h4>
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    disorientation, burning, convulsions. Contact with skin:
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    <h4>• Follow up DIKTI, BNI, MANDIRI, PGN dan KLH : BNI  dan Mandiri : <br>
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• BNI and Mandiri Bank told us that Our proposal has been given to the Corporate Secretary. <br>
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    irritation, disorientation. Eye contact: irritation, a burning
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• Our proposal has been given to the chief of High Education Office. The decision will be sent to the vice chancellor of academic and student affairs, <br>
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• Our proposal has been rejected by the The Ministry of Environment. They don't have the budget for this kind of research.<br>
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    sensation of the eyes, eye damage.
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• Indonesia State Gas Company : Our proposal is still in process.
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    Ethidium bromide will reduce the rate of migration of linear DNA
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<br> </h4>
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    molecules by 15%. This solution is extremely dangerous and
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                                        <h4><strong>25 September 2012</strong></h4>
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    carcinogenic. All solutions which contained ethidium bromide
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    <h4>• In the evening, we got news from Mandiri and BNI Bank that our proposal can't be accepted by the company.<br> </h4>
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    should be decontaminated before disposal. Ethidium Bromide
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    (EtBr) will fluoresce under UV exposure. These dyes can be added
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    to the gel and buffer so there is no staining after
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    electrophoresis process. The advantage is more practical, but
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    the possibility of EtBr contamination is greater. Due to the
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    carcinogenic factor, it must be avoided for direct contact.<br> </h4>
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    <h4><strong>Public Safety</strong><br></h4>
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    <h4>We have ethics to minimize the danger possibility to public. We
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    usually wear single-used gloves, covered shoes, lab coat, and
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    mask so the accumulation of materials and impurities are not
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    exposed to participant directly. We have a liquid discharge
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    valves which equipped with running water, so it won't settle. We
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    also have a separated solid waste disposal for potentially
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    hazardous materials. Those ethics are rules in our work on this
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    project. </h4>
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                                         <br>
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    <h4><strong>Environmental Safety</strong><br></h4>
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  <h4> No harmful effect on our enzyme product. E. coli bacteria which
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    inserted by  Cutinase gene has been set for its life period by
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    sonicator so there'll no blooming act in nature. Destruction of
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    PET by using our products is done at indoor laboratory so the  
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    waste does not impact to the environment directly. The enzyme
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    does not cause further effect especially for chemical / physical
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    danger.No harmful effect on our enzyme product. E. coli bacteria
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    which inserted by  Cutinase gene has been set for its life
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    period by sonicator so there'll no blooming act in nature.
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    Destruction of PET by using our products is done at indoor
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    laboratory so the waste does not impact to the environment
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    directly. The enzyme does not cause further effect especially
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      for chemical / physical danger.
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  </h4>                                     <br>
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  <h3> <strong>2. Do any of the new BioBrick parts (or devices) that you
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    made this year raise safety issues? If yes, Did you document these issues in the Registry?</strong> </h3><br>
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    <h4>No, we didn't document the safety issue to the registry, but our
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    procedure was according the Standard Operational Procedure of
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    Molecular Biology Laboratory and Microbiology laboratory in IPB
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    (Bogor Agricultural University). So we think our project hasn't
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    any safety risk during we follow the procedure carefully.</h4><br>  
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    <h4><strong>How did you manage to handle the safety issue?</strong></h4><br>
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  <h4> To handle the security issue of our work, we always consult with
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    the team advisor and instructor who handle the laboratory
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    security work in IPB. Our security is guaranteed by following
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    the standard operating procedures which provided in each
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    laboratory. As a mechanism to ensure the safety of our work,  
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    first of all we started it by product testing step in the
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    laboratory before applying it in nature, so when the result is
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    guaranteed safely, it can be applied in nature.</h4><br>  
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    <h4><strong>How could other teams learn from your experience?</strong></h4><br>
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  <h4> Other teams can learn from the procedure that we have used. We
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    use the common procedure that is used by molecular researchers
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    at the laboratory, so its safety has been tested (as long as we
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      follow the standard operation procedure had been given).                                    
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      </h4><br>
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    <h3><strong>3. Is there a local biosafety group, committee, or review
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    board at your institution? </strong><h3> <br>
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      <h4><strong>Which specific biosafety rules or guidelines do you have to
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    consider in your country?</strong></h4><br>
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  <h4> We have no local biosafety committee at our institution but
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    there are Biosafety rules or guidelines in our country. Please
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    see below :<br>
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    1. Regulation Law No. 32 of 2009 about Environmental
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    Protection & Management<br>  
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    2. Law No. 7 of 1996 on Food<br>
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    3. Law No. 18 of 2002 on National System
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    Research,Development and Application of Science and
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    Technology<br>
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    4. Law No. 18 of 2004 on Plantation<br>
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    5. Law No. 23 of 1992 on Health<br>
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    6. Law No. 23 of 1992 on Animal, Fish, and Plant
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    Quarantine<br>
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    7. Law No. 41 of 1999 on Forestry<br>
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    8. Government Regulation No. 21 of 2005 on Biosafety of
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    Genetically Engineered Product<br>
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    9. Presidential Decree 39 of 2010 on Biosafety Commision of
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    Genetically Engineered Product.<br>
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    10. INSTITUTIONAL ARRANGEMENT Biosafety Commision
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    Established by Presidential Decree No. 39/2010 <br>
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    11. Biosafety Technical Team In the establishment
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    process.<br>
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    12. Biosafety Clearing House Regarding Article 20 of the
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    Cartagena Protocol, Indonesia has been establish a Biosafety
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    Clearing House to facilitate the exchange of scientific,
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    technical , environmental and legalinformation on LMO. BCH is  
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    coordinated by Ministry of Environment in cooperation with
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    Indonesia Institute of Science Secretariat of Biosafety
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    Commission.<br>
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    13. Law 32/2009. Every activities may create important risk
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    on environment, biodiversity and human healthand human safety
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    have to carry out Environmental Risk Analysis, Risk Assessment,
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      Risk Management, Risk Communication.                                                                                                                   
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      </h4><br>
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        <h3><strong>4. Do you have any other ideas how to deal with safety
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        issues that could be useful for future iGEM competitions? How
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        could parts, devices and systems be made even safer through
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          biosafety engineering? </strong>
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      </h3>                                      <br>
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      <h4>To ensure the biosafety, it will be better to give more
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        certification letter about the safety of materials which
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        provided to the participants. Each institution must have their
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        own fire fighters and laboratory clinic centre.
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        To minimize the hazardous chemicals we can use the synthetic
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        biology engineered system. The equipment which is used is fairly
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        easy to control for these biosafety ethics. The example of
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        recommended system that has better security is JSA (Job Safety
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        Analyst).</h4>
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Revision as of 13:19, 26 September 2012


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Sponsorship Team Journey


09-15 Mei 2012

• Making the team delegate proposal: to be given to the High Education Office (the proposal has not been signed by the vice chancellor of academic and student affairs).

20 Juni 2012

• Sending proposals and cover letters into High Education Office (the proposal has not been signed by the vice chancellor of academic and student affairs).

24 Juni 2012

• Making sponsorship proposal.

23 Agustus 2012

• Sending proposal to BRI and BNI (Bank), The proposal has not been signed by the vice chancellor of academic and student affairs.

3 September 2012

• Following up proposal to the High Education Office. We got advice from the High Education Office to complete the proposal with the signature of vice chancellor of academic and student affairs. Our proposal to the BRI Bank had been rejected.

6 September 2012

• Following up to the bank (BRI & BNI), High Education Office. The proposal was still processed at BNI and BRI Bank. The proposal at High Education Office had been arrived at Public Division.

11 September 2012

• Making the new proposal and cover letters ( it has been signed by the Advisor, Dekan FMIPA The vice chancellor of academic and student affairs, Head of Department Biology)

13 September 2012

• Sending new proposal to the Bank (Mandiri & BNI), Indonesia State Gas Company, The Ministry of Environment. The proposal has been completed by the cover letters from Bogor Agricultural University.

24 September 2012

• Follow up DIKTI, BNI, MANDIRI, PGN dan KLH : BNI dan Mandiri :
• BNI and Mandiri Bank told us that Our proposal has been given to the Corporate Secretary.
• Our proposal has been given to the chief of High Education Office. The decision will be sent to the vice chancellor of academic and student affairs,
• Our proposal has been rejected by the The Ministry of Environment. They don't have the budget for this kind of research.
• Indonesia State Gas Company : Our proposal is still in process.

25 September 2012

• In the evening, we got news from Mandiri and BNI Bank that our proposal can't be accepted by the company.

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