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Team:St Andrews
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| - | <p> | + | <p>ω-3 fatty acid is critical in the human diet and paramount to maintaining health. The nutrient is only synthesized naturally in a handful of organisms (algae and oil-rich plants). Our team has successfully recreated the pathway for ω-3 production in <i>E. coli</i> using genes from the cyanobacteria <i>Synechocystis</i> and the trypanosomatid <i>Leishmania major</i>, despite the difficulty of working with membrane-bound proteins. Until now, synthetic ω-3 production has only been achieved in plants. |
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Revision as of 11:49, 25 September 2012
re source
University of St Andrews' team for 2012 International Genetically Engineered Machine competition
Alternative Omega-3 production and novel metal recovery methods
Metal binding protein
Precious and toxic metals from car catalysts frequently find their way into the environment. By developing metal-binding proteins, we can reverse metal aggregation on our roads. This not only reduces the environmental impact of personal transportation, but will proffer a new man-made mine of precious metals.
ω−3 Fatty acids synthesis
ω-3 fatty acid is critical in the human diet and paramount to maintaining health. The nutrient is only synthesized naturally in a handful of organisms (algae and oil-rich plants). Our team has successfully recreated the pathway for ω-3 production in E. coli using genes from the cyanobacteria Synechocystis and the trypanosomatid Leishmania major, despite the difficulty of working with membrane-bound proteins. Until now, synthetic ω-3 production has only been achieved in plants.
Scientific impact of iGEM
We investigate the relationship between the iGEM competition and the rest of the scientific community. Is iGEM really having scientific impact? How often, how fairly and by whom are iGEM teams cited? Does the iGEM competition result in scholarly articles being published? What can guarantee continued recognition within the SynBio community?
The mathematics of ω-3
We modelled fish population dynamics. Our result: if we continue fishing in the current manner, by 2100, only a fraction of present day biomass levels will remain. Yet, there is hope. Indeed, realizing Team St Andrews' alternative production of Omega-3 could be the measure necessary to save our seas. We investigate both the effect that alternative production can have on future fish biomass, as well as the practicalities of preserving life in this manner.
Sponsors
iGEM
The International Genetically Engineered Machine competition (iGEM) is the premiere undergraduate Synthetic Biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.
