Team:St Andrews

From 2012.igem.org

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                        <h2>Projects</h2> We are currently investigating two projects in the wet lab: one of which is the production of ω-3 fatty acids, and the second - making a selection of metal binding proteins.  Both projects  were inspired by the preservation of nature and the ability to re - source our resources for the future.  Mathematical and computational modelling is heavily reliant on the collection of data relating to past and present fish stocks. We combine data in new and novel ways in order to estimate the size and scale of the Omega 3 factories necessary to cope with future demand. 
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                        <h2>Human practices</h2> iGEM is known to be a large competition with hundreds of teams entering every year from all over the globe. But to what extent does their work get acknowledged? We are looking into how iGEM is cited in scientific articles, and how this affects its impact on the scientific community.
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                        <h2>Biobricks</h2> We are hoping to make biobricks capable of synthesizing ω-3 fatty acids as well as multiple biobricks capable of binding many metals with the aim of platinum group elements (PGE) and a selection of additional noble metals.
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                        <h2>Data</h2> The data that we are compiling is from varied sources of fish stocks and their nutritional content and compiling them into a single data set.  This set will include biomass, biomass fished, average ω-3 fatty acid content per kilogram, natural birth rates and natural death rates.  We will also look at the types of fish being fished, and so the time taken for them to reach maturity and the proportion of the species being fished.  With this data the modeling of fish stocks over a selected period can occur and will allow us to see the approximate time where the production of ω-3 fatty acids is viable, or more likely integral.
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Revision as of 14:38, 2 August 2012

St Andrews iGEM '12

StA iGEM Wiki 2012 - Home

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Lorem-ipsum-what!?

We're still working here, so things may change under your feet. Do feel free to browse though!
We're in week 9 / 10 of the iGEM project! The end is nigh! :D

The site will be all ready and presentable by autumn.

source

University of St Andrews team for the 2012 International Genetically Engineered Machine competition

Solving the resource problems of the twenty-first century

University of St Andrews coat of arms

Metal binding protein

Precious metals are costly and the effects of mining are frequently undesirable. At the same time platinum, from catalysts within our cars, literally crumbles away onto our road surfaces. The iGEM Team St Andrews are among the first to advance into the shaft of de novo research that is metal capture technology. Producing platinum-binding proteins in E. coli will provide a framework which can be modified to produce an extracellular membrane-bound binding site.

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ω−3 Fatty acids synthesis

ω-3 Fatty acids are an essential component of our diet and are para-mount to maintaining human health. Our team is recreating this synthetic pathway in E. coli, using genes from the cyanobacteria Synechocystis and the trypanosomatid Leishmania major. Combining the DNA code for elongase and desaturase enzymes, we can convert the plain fatty acid of E. coli into highly valuable ω-3 fatty acids.

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Scientific impact of iGEM

We investigate the relationship between the iGEM competition and the rest of the scientific community. Is iGEM really having scientific impact? How often, how fairly and by whom are iGEM teams cited?

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Modelling ω−3 depletion

We investigate the global effects of industrial omega-3 production from alternative sources using mathematical models. How quickly must this production be instated to preserve marine wildlife diversity? What happens if this is not done?

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Sponsors

iGEM

The International Genetically Engineered Machine competition (iGEM) is the premiere undergraduate Synthetic Biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.

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University of St Andrews, 2012.

Contact us: igem2012@st-andrews.ac.uk, Twitter, Facebook

This iGEM team has been funded by the MSD Scottish Life Sciences Fund. The opinions expressed by this iGEM team are those of the team members and do not necessarily represent those of Merck Sharp & Dohme Limited, nor its Affiliates.

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