Team:TU-Eindhoven/Notebook

From 2012.igem.org

(Difference between revisions)
 
Line 26: Line 26:
So finally we decided on our project... Yet it’s time to start our biggest challenge in science! Before the first week of the summer, the project of the iGEM team of <span class= "red">Valencia in 2009</span> was our basic guideline. We did not only read their wiki, but also considered their outlook, tips and bibliography. </p>
So finally we decided on our project... Yet it’s time to start our biggest challenge in science! Before the first week of the summer, the project of the iGEM team of <span class= "red">Valencia in 2009</span> was our basic guideline. We did not only read their wiki, but also considered their outlook, tips and bibliography. </p>
<p>
<p>
-
We discovered their use of a model of sympathetic ganglion `B' type cells of a bullfrog as described in Methods in Neuronal Modeling: From Synapses to Networks <html><a href="#ref_valencia" name="text_valencia"><sup>[1]</sup></a></html>. The large amount of Spanish comments in their <span class= "red">MATLAB model</span> made it even more difficult for us to understand the link between yeast cells and these neural cells, so therefore we decided to remake this model. We were able to do so, performed a complete parameter sensitivity analysis, tried to adapt this model to the characteristics of yeast cells and finally had to decide that this model simply does not fit the calcium homeostasis in yeast cells... :-( <span class= "red"> Let’s create a new model</span>...
+
We discovered their use of a model of sympathetic ganglion 'B' type cells of a bullfrog as described in Methods in Neuronal Modeling: From Synapses to Networks <html><a href="#ref_valencia" name="text_valencia"><sup>[1]</sup></a></html>. The large amount of Spanish comments in their <span class= "red">MATLAB model</span> made it even more difficult for us to understand the link between yeast cells and these neural cells, so therefore we decided to remake this model. We were able to do so, performed a complete parameter sensitivity analysis, tried to adapt this model to the characteristics of yeast cells and finally had to decide that this model simply does not fit the calcium homeostasis in yeast cells... :'-( <span class= "red"> Let's create a new model</span>...
</p>
</p>
<h3>
<h3>

Latest revision as of 22:34, 26 September 2012