Team:Fatih-Medical

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<h2>FreshEcoli</h2>
 
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Trimethylaminuria is a health disorder caused by the lack of the enzyme FMO-3. This disease ruins the social lives of people born with it. It causes the excretion of a disgusting fish odor.
 
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With our genetically modified E.coli, we would like to pursue the solution of this problem. By implementing the necessary system, we will offer a synthetic solution.
 
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</p>.
 
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<p>
 
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Our system is based on the removal of the disturbing odor caused by this disease. Also, the usage of the products of this process to make the bacteria release geraniol (which is the chemical that provides the rose its aroma) is also something else that we wish to do.
 
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</p>
 
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<p>
 
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With FreshEcoli project, we will get rid of bad odor and make a bacteria produce a nice fragrance. This will allow us to benefit from the good smell released, and also, remove the belief that bacteria smell unpleasant.
 
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<h2>FreshEcoli</h2>
+
-
<p>
+
-
Trimethylaminuria is a health disorder caused by the lack of the enzyme FMO-3. This disease ruins the social lives of people born with it. It causes the excretion of a disgusting fish odor.
+
-
With our genetically modified E.coli, we would like to pursue the solution of this problem. By implementing the necessary system, we will offer a synthetic solution.
+
-
</p>.
+
-
<p>
+
-
Our system is based on the removal of the disturbing odor caused by this disease. Also, the usage of the products of this process to make the bacteria release geraniol (which is the chemical that provides the rose its aroma) is also something else that we wish to do.
+
-
</p>
+
-
<p>
+
-
With FreshEcoli project, we will get rid of bad odor and make a bacteria produce a nice fragrance. This will allow us to benefit from the good smell released, and also, remove the belief that bacteria smell unpleasant.
+
-
</p>
+
-
</td>
+
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            <div class="label_text">
 +
                <p>Meet Fatih Medical 2012</p>
 +
            </div>
 +
        </li>
 +
 
 +
        <li>
 +
            <a href="https://2012.igem.org/Team:Fatih-Medical/Project"><img src="https://static.igem.org/mediawiki/2012/archive/f/f7/20120926112144!Sherlocoli_Overview_%281%29.png" class="block" /></a>
 +
            <div class="label_text">CTC Project At A Glance</div>
 +
        </li>
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        <li>
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            <a href="https://2012.igem.org/Team:Fatih-Medical/Human_Practice"><img src="https://static.igem.org/mediawiki/2012/archive/f/f7/20120926112229!Sherlocoli_Overview_%281%29.png" class="block" /></a>
 +
 
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            <div class="label_text">
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                <p>Challenge Accepted! Here's The Video!</p>
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            </div>
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        </li>
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            <a href="https://2012.igem.org/Team:Fatih-Medical/Human_Practice/Secret_Book"><img src="https://static.igem.org/mediawiki/2012/archive/f/f7/20120926112309!Sherlocoli_Overview_%281%29.png" class="block" /></a>
 +
 
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            <div class="label_text">
 +
                <p>Gorgeous Surprises From FM For All iGEMers </p>
 +
            </div>
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        </li>
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        <li>
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            <a href="https://2012.igem.org/Team:Fatih-Medical/Human_Practice"><img src="https://static.igem.org/mediawiki/2012/archive/f/f7/20120926113241!Sherlocoli_Overview_%281%29.png" class="block" /></a>
 +
 
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            <div class="label_text">
 +
                <p>iGEM For Everyone!</p>
 +
            </div>
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        </li>
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        <li>
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            <a href="https://2012.igem.org/Team:Fatih-Medical/Lab/Gallery"><img src="https://static.igem.org/mediawiki/2012/archive/f/f7/20120926114250!Sherlocoli_Overview_%281%29.png" class="block" /></a>
 +
 
 +
            <div class="label_text">
 +
                <p>Various Times, Various Memories</p>
 +
            </div>
 +
        </li>
 +
 
 +
 
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        <li>
 +
            <a href="http://fatih.edu.tr/"><img src="https://static.igem.org/mediawiki/2012/archive/f/f7/20120926113840!Sherlocoli_Overview_%281%29.png" class="block" /></a>
 +
 
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            <div class="label_text">
 +
                <p>Fatih University Campus</p>
 +
            </div>
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        </li>
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    </ul>
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</div>
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        <div class="wrapper">
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            <article class="grid_12">
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<map id="imgmap201292712257" name="imgmap201292712257"><area shape="rect" alt="" title="" coords="26,7,401,169" href="https://2012.igem.org/Team:Fatih-Medical/Sherlocoli" target="" /><area shape="rect" alt="" title="" coords="26,179,405,345" href="https://2012.igem.org/Team:Fatih-Medical/DJcoli" target="" /><area shape="rect" alt="" title="" coords="24,357,405,528" href="https://2012.igem.org/Team:Fatih-Medical/Dracoli" target="" /><!-- Created by Online Image Map Editor (http://www.maschek.hu/imagemap/index) --></map>
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<img usemap="#imgmap201292712257" src="https://static.igem.org/mediawiki/2012/6/66/Fatih-home-icons.png">
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            </article>
 +
 
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            <article class="grid_12">
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<h2>Cancel the Cancer: A SynBio Approach to the Early Diagnosis of Cancer </h2>
 +
<HR size="10" width="70%" align="left">
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  Our project is mainly based on the early diagnosis of cancer. EpCAM (Epithelial cell adhesion molecule) is a pan-epithelial differentiation antigen overexpressed on the basolateral surface of most carcinomas and Circulating Tumor Cells(CTC); cells which are released into blood in early phases of cancer. Our objective is to fix appropriate antibodies for EpCAM antigens to the E.coli cell wall so that we will be able to detect CTCs before the cancer precipitates its way to metastasis. For the next step, we plan to enhance the detection signal in our bacteria by the means of the quorum sensing mechanism. Finally, to prevent the production of possible undesirable and detrimental genetically modified organisms (GMOs), we aim to induce self-destruction device in our E.coli via emission of light.
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{{Template:Fatih-footer}}

Latest revision as of 00:44, 27 September 2012

  • Meet Fatih Medical 2012

  • CTC Project At A Glance

  • Challenge Accepted! Here's The Video!

  • Gorgeous Surprises From FM For All iGEMers

  • iGEM For Everyone!

  • Various Times, Various Memories

  • Fatih University Campus

Cancel the Cancer: A SynBio Approach to the Early Diagnosis of Cancer

Our project is mainly based on the early diagnosis of cancer. EpCAM (Epithelial cell adhesion molecule) is a pan-epithelial differentiation antigen overexpressed on the basolateral surface of most carcinomas and Circulating Tumor Cells(CTC); cells which are released into blood in early phases of cancer. Our objective is to fix appropriate antibodies for EpCAM antigens to the E.coli cell wall so that we will be able to detect CTCs before the cancer precipitates its way to metastasis. For the next step, we plan to enhance the detection signal in our bacteria by the means of the quorum sensing mechanism. Finally, to prevent the production of possible undesirable and detrimental genetically modified organisms (GMOs), we aim to induce self-destruction device in our E.coli via emission of light.
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