Team:St Andrews

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<h4 class="alert-heading">Lorem-ipsum-what!?</h4>
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<p>We're still working here, so things may change under your feet. Do feel free to browse though!
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<br/>We're in week 9 / 10 of the iGEM project! The end is nigh! :D</p>
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<p>The site will be all ready and presentable by autumn.</p>
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                 <p>University of St Andrews team for the 2012 <em>International Genetically Engineered Machine competition</em></p>
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                 <p>University of St Andrews' team for 2012 <em>International Genetically Engineered Machine competition</em></p>
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<p>Solving the resource problems of the twenty-first century</p>
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<p>Alternative omega-3 production and novel metal recovery methods</p>
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<h1>Metal binding protein</h1>
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<h1><a href="https://2012.igem.org/Team:St_Andrews/metal-binding">Metal binding protein</a></h1>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925002”><span class="badge">BBa_K925002</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925004”><span class="badge">BBa_K925004</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925005”><span class="badge">BBa_K925005</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925006”><span class="badge">BBa_K925006</span></a></button>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925007”><span class="badge">BBa_K925007</span></a></button>
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<img src="https://static.igem.org/mediawiki/2012/9/9f/MetalBindingLogo_100.png" align="left" />                 
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                <p>Precious metals are costly and the effects of mining are frequently undesirable. At the same time platinum, from catalysts within our cars, literally crumbles away onto our road surfaces. The iGEM Team St Andrews are among the first to advance into the shaft of de novo research that is metal capture technology. Producing platinum-binding proteins in E. coli will provide a framework which can be modified to produce an extracellular membrane-bound binding site.  
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<p>Precious and toxic metals from car catalysts frequently find their way into the
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environment. By developing metal-binding proteins, we can reverse metal aggregation on our roads. This not only reduces the environmental impact of personal transportation, but will proffer a new man-made mine of precious metals.</p>
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<p><a class="btn btn-large" href="https://2012.igem.org/Team:St_Andrews/metal-binding">Learn more</a></p>
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<!-- previous text: Precious metals often go unrecyled. Platinum used catalytic converters ends up in road dust. So much platinum accumulates on a 3km stretch of road in one year (60 grams) that it would sell for £2500! We envision engineered bacteria that help reclaim microscopic fragments of rare metals from these unusual sources.
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                <h1>ω−3 Fatty acids synthesis</h1>
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<h1><a href="https://2012.igem.org/Team:St_Andrews/Omega-3-synthesis">ω−3 fatty acids synthesis</a></h1>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925000”><span class="badge">BBa_K925000</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925001”><span class="badge">BBa_K925001</span></a>
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<img src="https://static.igem.org/mediawiki/2012/5/57/OmegaThreeLogo_100.png" align="left" />                 
<img src="https://static.igem.org/mediawiki/2012/5/57/OmegaThreeLogo_100.png" align="left" />                 
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           <p>     ω-3 Fatty acids are an essential component of our diet and are para-mount to maintaining human health. Our team is recreating this synthetic pathway in E. coli, using genes from the cyanobacteria Synechocystis and the trypanosomatid Leishmania major. Combining the DNA code for elongase and desaturase enzymes, we can convert the plain fatty acid of E. coli into highly valuable ω-3 fatty acids.  
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           <p>ω-3 fatty acid is a key component of the healthy human diet. The nutrient is only synthesized naturally in a handful of organisms (algae and oil-rich plants). Our team partially recreated the pathway for ω-3 production in <i>E. coli</i> using genes from the cyanobacteria <i>Synechocystis</i>, despite the difficulty of working with membrane-bound proteins. Until now, synthetic ω-3 production has only been achieved in plants.
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                <p><a class="btn btn-large" href="https://2012.igem.org/Team:St_Andrews/Omega-3-synthesis">Learn more</a></p>
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                <h1>Scientific impact of iGEM</h1>
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<h1><a href="https://2012.igem.org/Team:St_Andrews/Human-practices">Scientific impact of iGEM</a></h1>
<img src="https://static.igem.org/mediawiki/2012/a/ac/ImpactLogo_100.png" align="left" />
<img src="https://static.igem.org/mediawiki/2012/a/ac/ImpactLogo_100.png" align="left" />
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                 <p>We investigate the relationship between the iGEM competition and the rest of the scientific community. Is iGEM <em>really</em> having scientific impact? How often, how fairly and by whom are iGEM teams cited?</p>
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                 <p>We investigate the relationship between the iGEM competition and the rest of the scientific community. Is iGEM <em>really</em> having scientific impact? How often, how fairly and by whom are iGEM teams cited? Does the iGEM competition result in scholarly articles being published? What can guarantee continued recognition within the SynBio community?</p>
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                <p><a class="btn btn-large" href="https://2012.igem.org/Team:St_Andrews/Human-practices">Learn more</a></p>
 
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<h1><a href="https://2012.igem.org/Team:St_Andrews/Modelling">The mathematics of ω-3</a></h1>
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                <h1>Modelling ω−3 depletion</h1>
 
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                 <p>We investigate the global effects of industrial omega-3 production from alternative sources using mathematical models. How quickly must this production be instated to preserve marine wildlife diversity? What happens if this is not done?</p>
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                 <p>We modelled fish population dynamics. Our result: if we continue fishing in the current manner, by 2100, only a fraction of present day biomass will remain.  Yet, there is hope.  Indeed, realizing Team St Andrews' alternative production of omega-3 could be the measure necessary to save our seas.  We investigated the effect that alternative production can have on future fish biomass, as well as the practicalities of preserving life in this manner.</p>
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                <p><a class="btn btn-large" href="https://2012.igem.org/Team:St_Andrews/Modelling">Learn more</a></p>
 
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                         <li class="span3"><a href="http://www.lgcstandards.com/" class="thumbnail"><img src="http://dl.dropbox.com/u/491730/iGEm/images/sponsors/LGC.jpg" alt=""></a></li>
                         <li class="span3"><a href="http://www.lgcstandards.com/" class="thumbnail"><img src="http://dl.dropbox.com/u/491730/iGEm/images/sponsors/LGC.jpg" alt=""></a></li>
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                     <h1>iGEM</h1>
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                     <p>The International Genetically Engineered Machine competition (iGEM) is the premiere undergraduate Synthetic Biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.</p>
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                     <p>The International Genetically Engineered Machine competition (iGEM) is the premier undergraduate synthetic biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.</p>
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<h4 class="alert-heading">Offline project summaries</h4>
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These are the downloadable versions of our project summaries:
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                     <h3>Twitter</h3><br>
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                    <h3>News</h3>
 
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Latest revision as of 02:02, 23 October 2012

St Andrews iGEM '12

StA iGEM Wiki 2012 - Home

source

University of St Andrews' team for 2012 International Genetically Engineered Machine competition

Alternative omega-3 production and novel metal recovery methods

University of St Andrews coat of arms

Metal binding protein

BBa_K925002 BBa_K925004 BBa_K925005 BBa_K925006 BBa_K925007

Precious and toxic metals from car catalysts frequently find their way into the environment. By developing metal-binding proteins, we can reverse metal aggregation on our roads. This not only reduces the environmental impact of personal transportation, but will proffer a new man-made mine of precious metals.

ω−3 fatty acids synthesis

BBa_K925000 BBa_K925001 BBa_K925003

ω-3 fatty acid is a key component of the healthy human diet. The nutrient is only synthesized naturally in a handful of organisms (algae and oil-rich plants). Our team partially recreated the pathway for ω-3 production in E. coli using genes from the cyanobacteria Synechocystis, despite the difficulty of working with membrane-bound proteins. Until now, synthetic ω-3 production has only been achieved in plants.


Scientific impact of iGEM

We investigate the relationship between the iGEM competition and the rest of the scientific community. Is iGEM really having scientific impact? How often, how fairly and by whom are iGEM teams cited? Does the iGEM competition result in scholarly articles being published? What can guarantee continued recognition within the SynBio community?


The mathematics of ω-3

We modelled fish population dynamics. Our result: if we continue fishing in the current manner, by 2100, only a fraction of present day biomass will remain. Yet, there is hope. Indeed, realizing Team St Andrews' alternative production of omega-3 could be the measure necessary to save our seas. We investigated the effect that alternative production can have on future fish biomass, as well as the practicalities of preserving life in this manner.

Sponsors

iGEM

The International Genetically Engineered Machine competition (iGEM) is the premier undergraduate synthetic biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.

×

Offline project summaries

These are the downloadable versions of our project summaries:

Twitter


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University of St Andrews, 2012.

Contact us: igem2012@st-andrews.ac.uk, Twitter, Facebook

This iGEM team has been funded by the MSD Scottish Life Sciences Fund. The opinions expressed by this iGEM team are those of the team members and do not necessarily represent those of Merck Sharp & Dohme Limited, nor its Affiliates.

Retrieved from "http://2012.igem.org/Team:St_Andrews"