Team:TU-Eindhoven

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<h3>Welcome to the home page of the iGEM team of the Eindhoven University of Technology!</h3>
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Eindhoven, the city famous for its light bulbs, is the place where the roots of Dutch television lie. We, the iGEM team of the Eindhoven University of Technology, developed an innovative piece of <span class="yellow">electro-biological  equipment</span> which will replace your old television screen in the future! We proudly present to you...
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It's a <span class="yellow">multi-colored display</span>, in which genetically engineered <span class="yellow">yeast cells</span> are electrically stimulated to induce a fluorescent light response and consequently function as pixels. Since calcium takes the leading part in this process, the yeast cells are engineered with <span class="yellow">fluorescent calcium sensors</span> and <span class="yellow">extra voltage-gated calcium channels</span>.
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Please take a look around at our site! Besides all important issues with regard to our project, you can find more information about us, our outreach, our partners and of course some nice pictures! Enjoy!
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A team of students from different departments of the Eindhoven University of Technology participates in the International Genetically Engineered Machine competition 2012, a synthetic biology competition for undergraduate students. The aim of the project is to design and produce a multi-color display, in which genetically engineered yeast cells function as pixels. Calcium ions enter a yeast cell when electrically stimulated, which in turn can trigger a fluorescent response through a genetically engineered calcium sensor protein. This will require a thorough understanding of calcium homeostasis in yeast cells. To explore the calcium metabolism, enable the induction of fluorescence and control this fluorescence, laboratory work will be combined with computational modeling and the engineering of a control device. The team envisions a yeast cell that is able to emit light when probed by an electrical stimulus: the Light Emitting Cell (LEC). The aim of this project therefore is to engineer and build a prototype display from LECs.
 
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Telephone: +31 40 247 5559<br />
 
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Email: [mailto:igem@tue.nl '''igem@tue.nl''']
 
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Latest revision as of 23:32, 26 September 2012