Team:USTC-China

From 2012.igem.org

(Difference between revisions)
(→Project description)
 
(88 intermediate revisions not shown)
Line 1: Line 1:
-
==Project description==
+
<html xmlns="http://www.w3.org/1999/xhtml" xml:lang="en">
-
This year, USTC-China iGEMers are providing a novel immune system for
+
<head>
 +
<link rel="stylesheet" href="https://2012.igem.org/Team:USTC-China/basic.css?action=raw&ctype=text/css" type="text/css">
-
engineering bacteria to fight against the bacteriophage. We hope this
+
<link rel="stylesheet" href="https://2012.igem.org/Team:USTC-China/home.css?action=raw&ctype=text/css" type="text/css">
 +
<link href='http://fonts.googleapis.com/css?family=Dosis' rel='stylesheet' type='text/css'>
 +
<script type="text/javascript" src="https://2012.igem.org/Team:USTC-China/jquery-1.2.3.js?action=raw&ctype=text/javascript"></script>
 +
<script type="text/javascript" src="https://2012.igem.org/Team:USTC-China/jquery.easing.1.3.js?action=raw&ctype=text/javascript"></script>
 +
<script type="text/javascript" src="https://2012.igem.org/Team:USTC-China/jquery.kwicks-1.5.1.js?action=raw&ctype=text/javascript"></script>
-
artificial line of defeat with gene circuits can be of practical use in
+
<script type="text/javascript">
-
fermentation industry.  
+
$().ready(function() {
 +
$('.kwicks').kwicks({
 +
max : 200,
 +
duration: 800, 
 +
easing: 'easeOutQuint'
 +
});
 +
});
 +
</script>
-
Since the fermentation industry occurred, the phage infection has become
+
    <!--this is the top menu-->
-
a big threat to engineering bacteria. During mass production of dairy
+
<script type="text/javascript" src="2012.igem.org/Team:USTC-China/jsFlashVer.js"></script>
-
products, enzymes, amino acids, antibiotics and pesticides, the results
+
 +
   
 +
</head>
-
are unimaginable if the bacterias are infected by bacteriophages . The
+
<body>
-
bacterias will die abnormally and the infection will spread quickly.
 
-
Without any efficient action, tremendous loss will lie ahead. Nowadays,
 
-
common strategies for avoiding this catastrophe is to control the
+
<a name="top" id="top"></a>
 +
<div id="ustc">
 +
<a href="http://wcm.ustc.edu.cn/pub/en_new/" >
 +
<img src="https://static.igem.org/mediawiki/2012/7/7f/Ustc.png"
 +
alt="USTC"/>
 +
</a>
 +
</div>
-
conditions of the fermentation strictly. Also, people keep selecting
+
<div class="kwicks_container">
 +
  <ul class="kwicks">
 +
  <li id="kwick_1">
 +
  <a href="https://2012.igem.org/Team:USTC-China">Home
 +
  <h3>Front page</h3>
 +
    </a>
 +
  </li>
 +
  <li id="kwick_2">
 +
  <a href="https://2012.igem.org/Team:USTC-China/background">Project
 +
  <h3>lambda phage</h3>
 +
    </a>
 +
  </li>
 +
  <li id="kwick_3">
 +
  <a href="https://2012.igem.org/Team:USTC-China/results">Achievements
 +
  <h3>What we get</h3>
 +
    </a>
 +
  </li>
 +
  <li id="kwick_4">
 +
  <a href="https://2012.igem.org/Team:USTC-China/modeling">Modeling
 +
  <h3>Analytic</h3>
 +
    </a>
 +
  </li>
 +
  <li id="kwick_5">
 +
  <a href="https://2012.igem.org/Team:USTC-China/outreach">Outreach
 +
  <h3>HumanPractice</h3>
 +
    </a>
 +
  </li>
 +
  <li id="kwick_6">
 +
  <a href="https://2012.igem.org/Team:USTC-China/protocols">Notes
 +
  <h3>Daily Recordings</h3>
 +
    </a>
 +
  </li>
 +
  <li id="kwick_7">
 +
  <a href="https://2012.igem.org/Team:USTC-China/team">Team
 +
  <h3>Members</h3>
 +
    </a>
 +
  </li>
 +
  </ul>
 +
</div>
 +
<div id="welcome">
 +
<P>WELCOME TO THE WIKI OF USTC-CHINA IGEM TEAM! ENJOY YOUR EXPLORATION!</P>
 +
</div>
-
strains against phages. But all the strategies are time consuming and far
 
-
from once for all.
+
<div id="centercontent">
 +
<div align="center">
-
However, the engineering bacteria 2012 USTC-China iGEMers hope to
+
<object codebase="http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab#version=7,0,19,0"
 +
width="940" height="450" classid="clsid:D27CDB6E-AE6D-11cf-96B8-444553540000">
 +
  <param name="movie" value="https://static.igem.org/mediawiki/2012/6/69/Currencyshow.swf?data=https://2012.igem.org/Team:USTC-China/home.xml?action=raw&ctype=text/xml"/>
 +
  <param name="quality" value="high" />
 +
  <param name="wmode" value="transparent" />
 +
  <embed src="https://static.igem.org/mediawiki/2012/6/69/Currencyshow.swf?data=https://2012.igem.org/Team:USTC-China/home.xml?action=raw&ctype=text/xml"
 +
wmode="transparent" quality="high"
 +
pluginspage="http://www.macromedia.com/go/getflashplayer"
 +
type="application/x-shockwave-flash" width="940" height="450"></embed>
 +
</object>
-
cultivate both protecting themselves when bacteriophage invades the
+
</div>
-
strain and focusing on producing products without consuming extra energy
+
<div id="rightoption" style="float:right;width:275px;height:auto;z-index:100">
 +
<div id="optionone">
 +
<a href="https://2012.igem.org/Team:USTC-China/parts" class="one">PARTS</a>
 +
<p class="button">This summer we have contributed 22 parts to the partsregistry!</p>
 +
</div>
 +
<div id="option2" >
 +
<a href="https://2012.igem.org/Team:USTC-China/modeling">MODELING</a>
 +
<p class="button">We have theoretically analysed our system through Mathematical Modeling!</p>
 +
</div>
 +
<div id="option3" >
 +
<a href="https://2012.igem.org/Team:USTC-China/outreach">OUTREACH</a>
 +
<p class="button">Our team have conducted several activities for public recognition of synthetic biology!</p>
 +
</div>
 +
<div id="option4">
 +
<a href="https://2012.igem.org/Team:USTC-China/safety">SAFETY</a>
 +
<p class="button">The project is considered to have the minimal risks!</p>
 +
</div>
 +
<div id="option5" >
 +
<a href="https://2012.igem.org/Team:USTC-China/team">TEAM</a>
 +
<p class="button2">Members in USTC_China enjoyed themselves this summer!</p>
 +
</div>
 +
</div>
-
when their living environment is safe. In this case, the quality of
+
<div id="overview" style="background-color: #E8FFD1; -moz-border-radius: 20px;  -webkit-border-radius: 20px;border-radius: 20px; border: 1px solid #DDD; padding:15px;width:635px;height:530px;margin-left:20px;margin-right:0px;margin-top:20px;margin-bottom:20px;border:none;">
-
fermented products can be guaranteed and the profits of fermentation
+
<h3>WELCOME!</h3>
 +
<hr/>
 +
<img src="https://static.igem.org/mediawiki/2012/8/84/Project_overview.jpg" style="float:right;width:300px;height:225px;margin:15px;"  />
 +
<p class="project">Bacteriophage is one of the severest threats to fermentation factories. To help solve the problem, we design a gene circuit which can both sense and defend against phages. We use the modified promoter pRM to sense the phage’s infection and initiate the defence. The lysis gene which can make bacteria lyse is installed to our circuit. When it works, the phage won’t be able to take advantage of its host to replicate any longer. To win more time for lysis to function well, we design an antisense RNA to prevent the phage from turning into lytic life cycle. Thus, when the lysis protein kills the host, the phage is still at lysogenic life cycle or the newly assembled phages are still immature. By using the quorum sensing system, the bacteria around the host can make well preparation to defend in advance. Attribute to these parts, our bacteria survive.</p>
 +
<br>
-
industry can be enormously improved.
+
<div class="more" style="padding:5px;width:150px;height:30px;margin-left:500px;">
-
[[File:Project Map.jpg]]
+
<p class="button"><a href="https://2012.igem.org/Team:USTC-China/background">more</a></p>
 +
</div>
 +
</div>
 +
<div id="ustcsponsor" >
 +
  <p class="big">SPONSORS</p></br>
 +
  <a href="http://china.db.com/" style="float:left;margin-left:10px;"><img src="https://static.igem.org/mediawiki/2012/0/0c/Deutsche_bank.jpg" /></a>
 +
  <a href="http://www.ustcif.org/" ><img src="https://static.igem.org/mediawiki/2012/3/36/Ustcif.jpg" style="height:99px;width:98px;float:left;margin-left:10px;"/></a>
 +
  <a href="http://en.gradschool.ustc.edu.cn/" ><img src="https://static.igem.org/mediawiki/2012/7/79/GRADUATE.png" style="float:left;margin-left:10px;"/></a>
 +
  <a href="http://www.teach.ustc.edu.cn/" style="float:left;margin-left:10px;"><img src="https://static.igem.org/mediawiki/2012/7/79/Teaching.jpg" /></a>
 +
  <a href="http://en.biox.ustc.edu.cn/" style="float:left;margin-left:10px;"><img src="https://static.igem.org/mediawiki/2012/archive/5/5e/20120830175936%21Life.jpg" /></a>
 +
  <a href="http://en.physics.ustc.edu.cn/" style="float:left;margin-left:10px;"><img src="https://static.igem.org/mediawiki/2012/a/ac/Phy.png" /></a>
 +
  <a href="http://en.scgy.ustc.edu.cn/" ><img src="https://static.igem.org/mediawiki/2012/f/f1/Gifted_young.jpg" style="width:330px;height:85px;float:left;margin-left:10px;"/></a>
 +
</div>
 +
</div><!--the centercontent-->
 +
 
 +
 
 +
 
 +
<!--the top menu-->
 +
<div class="returnTop" show="true" style="visibility: visible; zoom: 1; opacity: 1; ">
 +
<a href="#top">backtotop</a></div>

Latest revision as of 03:21, 28 September 2013

WELCOME TO THE WIKI OF USTC-CHINA IGEM TEAM! ENJOY YOUR EXPLORATION!

PARTS

This summer we have contributed 22 parts to the partsregistry!

MODELING

We have theoretically analysed our system through Mathematical Modeling!

OUTREACH

Our team have conducted several activities for public recognition of synthetic biology!

SAFETY

The project is considered to have the minimal risks!

TEAM

Members in USTC_China enjoyed themselves this summer!

WELCOME!

Bacteriophage is one of the severest threats to fermentation factories. To help solve the problem, we design a gene circuit which can both sense and defend against phages. We use the modified promoter pRM to sense the phage’s infection and initiate the defence. The lysis gene which can make bacteria lyse is installed to our circuit. When it works, the phage won’t be able to take advantage of its host to replicate any longer. To win more time for lysis to function well, we design an antisense RNA to prevent the phage from turning into lytic life cycle. Thus, when the lysis protein kills the host, the phage is still at lysogenic life cycle or the newly assembled phages are still immature. By using the quorum sensing system, the bacteria around the host can make well preparation to defend in advance. Attribute to these parts, our bacteria survive.


more

SPONSORS


backtotop

Retrieved from "http://2012.igem.org/Team:USTC-China"