Team:St Andrews

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     <title>StA iGEM Wiki 2012 - Home</title>
     <title>StA iGEM Wiki 2012 - Home</title>
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<h4 class="alert-heading">Lorem-ipsum-what?</h4>
 
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This website is under construction, but feel free to browse! It'll be completely ready by autumn.
 
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We're in week 5 out of 10 of the iGEM project.
 
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                 <h1>St Andrews iGEM 2012</h1>
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                 <p>University of St Andrews' team for 2012 <em>International Genetically Engineered Machine competition</em></p>
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                 <p>University of St Andrews team for the 2012 <em>International Genetically Engineered Machine competition</em></p>
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<p>Alternative omega-3 production and novel metal recovery methods</p>
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             <div class="span2"><img src="https://static.igem.org/mediawiki/2012/a/ad/Crest.gif" alt="University of St Andrews coat of arms"></div>
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<h1>Metal binding protein</h1>
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<h1><a href="https://2012.igem.org/Team:St_Andrews/metal-binding">Metal binding protein</a></h1>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925002”><span class="badge">BBa_K925002</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925004”><span class="badge">BBa_K925004</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925005”><span class="badge">BBa_K925005</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925006”><span class="badge">BBa_K925006</span></a></button>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925007”><span class="badge">BBa_K925007</span></a></button>
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<img src="https://static.igem.org/mediawiki/2012/9/9f/MetalBindingLogo_100.png" align="left" />                 
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<p>Precious and toxic metals from car catalysts frequently find their way into the
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environment. By developing metal-binding proteins, we can reverse metal aggregation on our roads. This not only reduces the environmental impact of personal transportation, but will proffer a new man-made mine of precious metals.</p>
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                <p>Precious metals often go unrecyled. Platinum used catalytic converters ends up in road dust. So much platinum accumulates on a 3km stretch of road in one year (60 grams) that it would sell for £2500! We envision engineered bacteria that help reclaim microscopic fragments of rare metals from these unusual sources.</p>
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                <p><a class="btn btn-large" href="https://2012.igem.org/Team:St_Andrews/metal-binding">Learn more</a></p>
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                <h1>ω−3 fatty acids synthesis</h1>
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<h1><a href="https://2012.igem.org/Team:St_Andrews/Omega-3-synthesis">ω−3 fatty acids synthesis</a></h1>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925000”><span class="badge">BBa_K925000</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925001”><span class="badge">BBa_K925001</span></a>
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<a href=”http://partsregistry.org/wiki/index.php?title=Part:BBa_K925003”><span class="badge">BBa_K925003</span></a>
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<img src="https://static.igem.org/mediawiki/2012/5/57/OmegaThreeLogo_100.png" align="left" />                 
<img src="https://static.igem.org/mediawiki/2012/5/57/OmegaThreeLogo_100.png" align="left" />                 
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          <p>ω-3 fatty acid is a key component of the healthy human diet. The nutrient is only synthesized naturally in a handful of organisms (algae and oil-rich plants). Our team partially recreated the pathway for ω-3 production in <i>E. coli</i> using genes from the cyanobacteria <i>Synechocystis</i>, despite the difficulty of working with membrane-bound proteins. Until now, synthetic ω-3 production has only been achieved in plants. 
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                <p>Omega-3 fatty acids are an essential nutrient. Fish (currently the best source) is severely overexploited. An alternative source of it would help in the environmental battle against overfishing. We attempt to engineer an omega-3 pathway into the bacterium <em>E. coli.</em> in the hopes that omega-3 could be produced at industrial scale.</p>
 
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                <h1>Scientific impact of iGEM</h1>
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<h1><a href="https://2012.igem.org/Team:St_Andrews/Human-practices">Scientific impact of iGEM</a></h1>
<img src="https://static.igem.org/mediawiki/2012/a/ac/ImpactLogo_100.png" align="left" />
<img src="https://static.igem.org/mediawiki/2012/a/ac/ImpactLogo_100.png" align="left" />
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<p></p>
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                <p>We investigate the relationship between the iGEM competition and the rest of the scientific community. Is iGEM <em>really</em> having scientific impact? How often, how fairly and by whom are iGEM teams cited? Does the iGEM competition result in scholarly articles being published? What can guarantee continued recognition within the SynBio community?</p>
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                <p>We investigate the relationship between the iGEM competition and the rest of the scientific community. Is iGEM <em>really</em> having scientific impact? How often, how fairly and by whom are iGEM teams cited?</p>
 
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                <p><a class="btn btn-large">Learn more</a></p>
 
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<h1><a href="https://2012.igem.org/Team:St_Andrews/Modelling">The mathematics of ω-3</a></h1>
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                <h1>Modeling ω−3 depletion</h1>
 
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<img src="https://static.igem.org/mediawiki/2012/f/f0/ModSquadLogo_100.png" align="left" />
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                <p>We modelled fish population dynamics. Our result: if we continue fishing in the current manner, by 2100, only a fraction of present day biomass will remain.  Yet, there is hope.  Indeed, realizing Team St Andrews' alternative production of omega-3 could be the measure necessary to save our seas.  We investigated the effect that alternative production can have on future fish biomass, as well as the practicalities of preserving life in this manner.</p>
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                <p>We investigate the global effects of industrial omega-3 production from alternative sources using mathematical models. How quickly must this production be instated to preserve marine wildlife diversity? What happens if this is not done?</p>
 
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                <p><a class="btn btn-large">Learn more</a></p>
 
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                        <h2>Projects</h2>Lorem ipsum dolor sit amet, consectetur adipiscing elit. In lobortis elit facilisis odio egestas dictum. Donec sed orci quis nibh suscipit aliquam. Mauris a risus nisl. Ut vel lorem mauris. Integer et arcu ut tellus cursus rhoncus at sed lorem. Phasellus imperdiet, est quis sagittis laoreet, eros ante tristique magna, sed auctor lorem quam et lectus. Quisque ac sem sit amet nisl consectetur iaculis.
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                         <li class="span3"><a href="http://www.lgcstandards.com/" class="thumbnail"><img src="http://dl.dropbox.com/u/491730/iGEm/images/sponsors/LGC.jpg" alt=""></a></li>
                         <li class="span3"><a href="http://www.lgcstandards.com/" class="thumbnail"><img src="http://dl.dropbox.com/u/491730/iGEm/images/sponsors/LGC.jpg" alt=""></a></li>
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                        <li class="span3"><a href="http://www.msd-uk.com/" class="thumbnail"><img src="https://static.igem.org/mediawiki/2012/b/b7/Msd.png" alt=""></a></li>
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                     <h1>iGEM</h1>
                     <h1>iGEM</h1>
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                     <p>The International Genetically Engineered Machine competition (iGEM) is the premiere undergraduate Synthetic Biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.</p>
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                     <p>The International Genetically Engineered Machine competition (iGEM) is the premier undergraduate synthetic biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.</p>
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<h4 class="alert-heading">Offline project summaries</h4>
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These are the downloadable versions of our project summaries:
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                     <h3>Twitter</h3><br>
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                     <h1>Twitter</h1><br>
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                    <h3>News</h3>
 
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Latest revision as of 02:02, 23 October 2012

StA iGEM Wiki 2012 - Home

source

University of St Andrews' team for 2012 International Genetically Engineered Machine competition

Alternative omega-3 production and novel metal recovery methods

University of St Andrews coat of arms

Metal binding protein

Precious and toxic metals from car catalysts frequently find their way into the environment. By developing metal-binding proteins, we can reverse metal aggregation on our roads. This not only reduces the environmental impact of personal transportation, but will proffer a new man-made mine of precious metals.

ω−3 fatty acids synthesis

ω-3 fatty acid is a key component of the healthy human diet. The nutrient is only synthesized naturally in a handful of organisms (algae and oil-rich plants). Our team partially recreated the pathway for ω-3 production in E. coli using genes from the cyanobacteria Synechocystis, despite the difficulty of working with membrane-bound proteins. Until now, synthetic ω-3 production has only been achieved in plants.


Scientific impact of iGEM

We investigate the relationship between the iGEM competition and the rest of the scientific community. Is iGEM really having scientific impact? How often, how fairly and by whom are iGEM teams cited? Does the iGEM competition result in scholarly articles being published? What can guarantee continued recognition within the SynBio community?


The mathematics of ω-3

We modelled fish population dynamics. Our result: if we continue fishing in the current manner, by 2100, only a fraction of present day biomass will remain. Yet, there is hope. Indeed, realizing Team St Andrews' alternative production of omega-3 could be the measure necessary to save our seas. We investigated the effect that alternative production can have on future fish biomass, as well as the practicalities of preserving life in this manner.


Sponsors

iGEM

The International Genetically Engineered Machine competition (iGEM) is the premier undergraduate synthetic biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.

×

Offline project summaries

These are the downloadable versions of our project summaries:

Twitter


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University of St Andrews, 2012.

Contact us: igem2012@st-andrews.ac.uk, Twitter, Facebook

This iGEM team has been funded by the MSD Scottish Life Sciences Fund. The opinions expressed by this iGEM team are those of the team members and do not necessarily represent those of Merck Sharp & Dohme Limited, nor its Affiliates.